CANDIDATE ID: 154

CANDIDATE ID: 154

NUMBER OF GENES: 10
AVERAGE SCORE:    9.9927204e-1 (range=[0.0,1.0])
AVERAGE MINIMUM BLAST P-VAL:    1.0000000e+0

Gene List
List of organisms containing most genes from the group
    Phylogenetic tree highlighting these organisms (opens new page)
List of organisms containing very few or no genes from the group
List of organisms enriched for group
List of organisms depleted for group
Phylogenetic profile similarity with known pathways
Pairwise genome context scores
Pairwise Blast scores
Pathway or protein complex matches in target organism
Genome context matrix
    Genes and their orthologs in genome browser BioCyc pages




GENE LIST:

- G7699 (yrdD) (b3283)
   Products of gene:
     - G7699-MONOMER (predicted DNA topoisomerase)

- G7698 (rimN) (b3282)
   Products of gene:
     - G7698-MONOMER (protein involved in synthesis of threonylcarbamoyladenosine-modified tRNA)

- G7697 (yrdB) (b3280)
   Products of gene:
     - G7697-MONOMER (conserved protein)

- EG12163 (rsmB) (b3289)
   Products of gene:
     - EG12163-MONOMER (16S rRNA m5C967 methyltransferase)
       Reactions:
        cytosine967 in 16S rRNA + S-adenosyl-L-methionine  ->  5-methylcytosine967 in 16S rRNA + S-adenosyl-L-homocysteine

- EG11605 (smg) (b3284)
   Products of gene:
     - EG11605-MONOMER (conserved protein)

- EG11604 (smf) (b3286 (obsolete))
   Products of gene:
     - EG11604-MONOMER (conserved protein)

- EG11440 (def) (b3287)
   Products of gene:
     - EG11440-MONOMER (peptide deformylase)
       Reactions:
        formyl-L-methionyl peptide + H2O  ->  methionyl peptide + formate + H+

- EG11268 (fmt) (b3288)
   Products of gene:
     - EG11268-MONOMER (10-formyltetrahydrofolate:L-methionyl-tRNAfMet N-formyltransferase)
       Reactions:
        L-methionyl-tRNAfmet + 10-formyl-tetrahydrofolate + H2O  ->  N-formyl-L-methionyl-tRNAfmet + tetrahydrofolate

- EG11019 (trkA) (b3290)
   Products of gene:
     - TRKA-MONOMER (NAD-binding component of TrK potassium transporter)

- EG10077 (aroE) (b3281)
   Products of gene:
     - AROE-MONOMER (shikimate dehydrogenase)
       Reactions:
        NADP+ + shikimate  =  NADPH + 3-dehydroshikimate + H+
         In pathways
         PWY-6165 (PWY-6165)
         ALL-CHORISMATE-PWY (superpathway of chorismate)
         COMPLETE-ARO-PWY (superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis)
         PWY-6163 (PWY-6163)
         ARO-PWY (chorismate biosynthesis I)



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ORGANISMS CONTAINING AT LEAST 9 GENES FROM THE GROUP:

Total number of orgs: 75
Effective number of orgs (counting one per cluster within 468 clusters): 38

Organism list
Homologs in each organism in the list
Features enriched in organism list


Follow (ncbi) link, when present, to find the set of organism features for each organism
Org ID  Org Name  # genes in group found in org  
YPSE349747 ncbi Yersinia pseudotuberculosis IP 317589
YPSE273123 ncbi Yersinia pseudotuberculosis IP 329539
YPES386656 ncbi Yersinia pestis Pestoides F9
YPES377628 ncbi Yersinia pestis Nepal5169
YPES360102 ncbi Yersinia pestis Antiqua9
YPES349746 ncbi Yersinia pestis Angola9
YPES214092 ncbi Yersinia pestis CO929
YPES187410 ncbi Yersinia pestis KIM 109
YENT393305 ncbi Yersinia enterocolitica enterocolitica 80819
VVUL216895 ncbi Vibrio vulnificus CMCP610
VVUL196600 ncbi Vibrio vulnificus YJ01610
VPAR223926 ncbi Vibrio parahaemolyticus RIMD 221063310
VFIS312309 ncbi Vibrio fischeri ES1149
VCHO345073 ncbi Vibrio cholerae O39510
VCHO ncbi Vibrio cholerae O1 biovar El Tor str. N1696110
STYP99287 ncbi Salmonella enterica enterica serovar Typhimurium str. LT210
SSP94122 ncbi Shewanella sp. ANA-310
SSON300269 ncbi Shigella sonnei Ss0469
SSED425104 ncbi Shewanella sediminis HAW-EB310
SPRO399741 ncbi Serratia proteamaculans 5689
SPEA398579 ncbi Shewanella pealeana ATCC 70034510
SONE211586 ncbi Shewanella oneidensis MR-110
SLOI323850 ncbi Shewanella loihica PV-410
SHIGELLA ncbi Shigella flexneri 2a str. 2457T10
SHAL458817 ncbi Shewanella halifaxensis HAW-EB410
SGLO343509 ncbi Sodalis glossinidius morsitans9
SFLE373384 ncbi Shigella flexneri 5 str. 84019
SFLE198214 ncbi Shigella flexneri 2a str. 30110
SENT454169 ncbi Salmonella enterica enterica serovar Heidelberg str. SL47610
SENT321314 ncbi Salmonella enterica enterica serovar Choleraesuis str. SC-B6710
SENT295319 ncbi Salmonella enterica enterica serovar Paratyphi A str. ATCC 915010
SENT220341 ncbi Salmonella enterica enterica serovar Typhi str. CT1810
SENT209261 ncbi Salmonella enterica enterica serovar Typhi str. Ty210
SDYS300267 ncbi Shigella dysenteriae Sd19710
SDEN318161 ncbi Shewanella denitrificans OS2179
SBOY300268 ncbi Shigella boydii Sb22710
SBAL402882 ncbi Shewanella baltica OS18510
SBAL399599 ncbi Shewanella baltica OS19510
PPRO298386 ncbi Photobacterium profundum SS910
PLUM243265 ncbi Photorhabdus luminescens laumondii TTO19
PING357804 ncbi Psychromonas ingrahamii 379
PHAL326442 ncbi Pseudoalteromonas haloplanktis TAC12510
PATL342610 ncbi Pseudoalteromonas atlantica T6c9
NMEN374833 ncbi Neisseria meningitidis 0534429
NMEN272831 ncbi Neisseria meningitidis FAM189
NMEN122587 ncbi Neisseria meningitidis Z24919
NMEN122586 ncbi Neisseria meningitidis MC589
NGON242231 ncbi Neisseria gonorrhoeae FA 10909
MCAP243233 ncbi Methylococcus capsulatus Bath9
KPNE272620 ncbi Klebsiella pneumoniae pneumoniae MGH 7857810
ILOI283942 ncbi Idiomarina loihiensis L2TR9
ESP42895 Enterobacter sp.10
EFER585054 ncbi Escherichia fergusonii ATCC 354699
ECOO157 ncbi Escherichia coli O157:H7 EDL93310
ECOL83334 Escherichia coli O157:H710
ECOL585397 ncbi Escherichia coli ED1a10
ECOL585056 ncbi Escherichia coli UMN02610
ECOL585055 ncbi Escherichia coli 5598910
ECOL585035 ncbi Escherichia coli S8810
ECOL585034 ncbi Escherichia coli IAI110
ECOL481805 ncbi Escherichia coli ATCC 873910
ECOL469008 ncbi Escherichia coli BL21(DE3)10
ECOL439855 ncbi Escherichia coli SMS-3-510
ECOL413997 ncbi Escherichia coli B str. REL60610
ECOL409438 ncbi Escherichia coli SE1110
ECOL405955 ncbi Escherichia coli APEC O19
ECOL364106 ncbi Escherichia coli UTI8910
ECOL362663 ncbi Escherichia coli 53610
ECOL331111 ncbi Escherichia coli E24377A10
ECOL316407 ncbi Escherichia coli K-12 substr. W311010
ECOL199310 ncbi Escherichia coli CFT07310
ECAR218491 ncbi Pectobacterium atrosepticum SCRI104310
CPSY167879 ncbi Colwellia psychrerythraea 34H9
ASAL382245 ncbi Aeromonas salmonicida salmonicida A44910
AHYD196024 Aeromonas hydrophila dhakensis10


Names of the homologs of the genes in the group in each of these orgs
  G7699   G7698   G7697   EG12163   EG11605   EG11604   EG11440   EG11268   EG11019   EG10077   
YPSE349747 YPSIP31758_3879YPSIP31758_3878YPSIP31758_3884YPSIP31758_3880YPSIP31758_3881YPSIP31758_3882YPSIP31758_3883YPSIP31758_3885YPSIP31758_3877
YPSE273123 YPTB3662YPTB3661YPTB3667YPTB3663YPTB3664YPTB3665YPTB3666YPTB3668YPTB3660
YPES386656 YPDSF_0167YPDSF_0168YPDSF_0162YPDSF_0166YPDSF_0165YPDSF_0164YPDSF_0163YPDSF_0161YPDSF_0169
YPES377628 YPN_3824YPN_3823YPN_3829YPN_3825YPN_3826YPN_3827YPN_3828YPN_3830YPN_3822
YPES360102 YPA_3228YPA_3227YPA_3233YPA_3229YPA_3230YPA_3231YPA_3232YPA_3234YPA_3226
YPES349746 YPANGOLA_A0620YPANGOLA_A0621YPANGOLA_A0613YPANGOLA_A0619YPANGOLA_A0616YPANGOLA_A0615YPANGOLA_A0614YPANGOLA_A0612YPANGOLA_A0622
YPES214092 YPO0245YPO0245AYPO0240YPO0244YPO0243YPO0242YPO0241YPO0239YPO0246
YPES187410 Y4026Y4027Y4021Y4025Y4024Y4023Y4022Y4020Y4028
YENT393305 YE3886YE3885YE3891YE3887YE3888YE3889YE3890YE3892YE3884
VVUL216895 VV1_1052VV1_1055VV1_1058VV1_1046VV1_1051VV1_1050VV1_1048VV1_1047VV1_1045VV1_1057
VVUL196600 VV3221VV3217VV3214VV3227VV3222VV3223VV3225VV3226VV3228VV3215
VPAR223926 VP3038VP3035VP3032VP3044VP3039VP3040VP3042VP3043VP3045VP3033
VFIS312309 VF2539VF2536VF2545VF2540VF2541VF2543VF2544VF2546VF2535
VCHO345073 VC0395_A2469VC0395_A2466VC0395_A2462VC0395_A2475VC0395_A2470VC0395_A2471VC0395_A2473VC0395_A2474VC0395_A2476VC0395_A2464
VCHO VC0050VC0054VC0057VC0044VC0049VC0048VC0046VC0045VC0043VC0056
STYP99287 STM3403STM3402STM3400STM3408STM3404STM3405STM3406STM3407STM3409STM3401
SSP94122 SHEWANA3_0039SHEWANA3_0040SHEWANA3_0044SHEWANA3_0033SHEWANA3_0038SHEWANA3_0037SHEWANA3_0035SHEWANA3_0034SHEWANA3_0032SHEWANA3_0043
SSON300269 SSO_3423SSO_3421SSO_3429SSO_3425SSO_3426SSO_3427SSO_3428SSO_3430SSO_3422
SSED425104 SSED_0040SSED_0041SSED_0044SSED_0033SSED_0038SSED_0037SSED_0035SSED_0034SSED_0032SSED_0043
SPRO399741 SPRO_4508SPRO_4507SPRO_4513SPRO_4509SPRO_4510SPRO_4511SPRO_4512SPRO_4514SPRO_4506
SPEA398579 SPEA_0036SPEA_0037SPEA_0041SPEA_0029SPEA_0034SPEA_0033SPEA_0031SPEA_0030SPEA_0028SPEA_0040
SONE211586 SO_0036SO_0037SO_0041SO_0030SO_0035SO_0034SO_0032SO_0031SO_0029SO_0040
SLOI323850 SHEW_3731SHEW_3730SHEW_3726SHEW_3738SHEW_3733SHEW_3734SHEW_3736SHEW_3737SHEW_3739SHEW_3727
SHIGELLA YRDDYRDCYRDBSUNSMGSMFDEFFMTTRKAAROE
SHAL458817 SHAL_0032SHAL_0033SHAL_0036SHAL_0025SHAL_0030SHAL_0029SHAL_0027SHAL_0026SHAL_0024SHAL_0035
SGLO343509 SG2244SG2243SG2241SG2248SG2245SG2246SG2247SG2249SG2242
SFLE373384 SFV_3303SFV_3301SFV_3308SFV_3304SFV_3305SFV_3306SFV_3307SFV_3309SFV_3302
SFLE198214 AAN44778.1AAN44777.1AAN44775.1AAN44783.1AAN44779.1AAN44780.1AAN44781.1AAN44782.1AAN44784.1AAN44776.1
SENT454169 SEHA_C3707SEHA_C3706SEHA_C3704SEHA_C3712SEHA_C3708SEHA_C3709SEHA_C3710SEHA_C3711SEHA_C3713SEHA_C3705
SENT321314 SCH_3339SCH_3338SCH_3336SCH_3344SCH_3340SCH_3341SCH_3342SCH_3343SCH_3345SCH_3337
SENT295319 SPA3270SPA3269SPA3267SPA3275SPA3271SPA3272SPA3273SPA3274SPA3276SPA3268
SENT220341 STY4394STY4395STY4397STY4389STY4393STY4392STY4391STY4390STY4388STY4396
SENT209261 T4101T4102T4104T4096T4100T4099T4098T4097T4095T4103
SDYS300267 SDY_3460SDY_3459SDY_3457SDY_3465SDY_3461SDY_3462SDY_3463SDY_3464SDY_3466SDY_3458
SDEN318161 SDEN_0028SDEN_0029SDEN_0022SDEN_0027SDEN_0026SDEN_0024SDEN_0023SDEN_0021SDEN_0034
SBOY300268 SBO_3277SBO_3276SBO_3274SBO_3282SBO_3278SBO_3279SBO_3280SBO_3281SBO_3283SBO_3275
SBAL402882 SHEW185_0031SHEW185_0032SHEW185_0036SHEW185_0025SHEW185_0030SHEW185_0029SHEW185_0027SHEW185_0026SHEW185_0024SHEW185_0035
SBAL399599 SBAL195_0035SBAL195_0036SBAL195_0040SBAL195_0029SBAL195_0034SBAL195_0033SBAL195_0031SBAL195_0030SBAL195_0028SBAL195_0039
PPRO298386 PBPRA3575PBPRA3573PBPRA3570PBPRA3581PBPRA3576PBPRA3577PBPRA3579PBPRA3580PBPRA3582PBPRA3571
PLUM243265 PLU4693PLU4692PLU4690PLU4697PLU4694PLU4695PLU4696PLU4698PLU4691
PING357804 PING_0074PING_0072PING_0080PING_0075PING_0076PING_0078PING_0079PING_0081PING_0071
PHAL326442 PSHAA0027PSHAA0028PSHAA0032PSHAA0021PSHAA0026PSHAA0025PSHAA0023PSHAA0022PSHAA0020PSHAA0031
PATL342610 PATL_0027PATL_0028PATL_0021PATL_0026PATL_0025PATL_0023PATL_0022PATL_0020PATL_0031
NMEN374833 NMCC_2030NMCC_2108NMCC_2036NMCC_2031NMCC_2032NMCC_2039NMCC_2038NMCC_1520NMCC_1783
NMEN272831 NMC0110NMC2128NMC0104NMC0109NMC0108NMC0102NMC0103NMC1535NMC1810
NMEN122587 NMA0156NMA0237NMA0162NMA0157NMA0158NMA0164NMA0163NMA1813NMA2129
NMEN122586 NMB_0118NMB_2150NMB_0112NMB_0117NMB_0116NMB_0110NMB_0111NMB_1614NMB_0358
NGON242231 NGO1863NGO1940NGO1869NGO1864NGO1865NGO1871NGO1870NGO1154NGO1602
MCAP243233 MCA_2839MCA_2838MCA_2845MCA_2840MCA_2841MCA_2843MCA_2844MCA_2849MCA_2794
KPNE272620 GKPORF_B3024GKPORF_B3023GKPORF_B3020GKPORF_B3029GKPORF_B3025GKPORF_B3026GKPORF_B3027GKPORF_B3028GKPORF_B3030GKPORF_B3022
ILOI283942 IL0021IL0022IL0016IL0020IL0019IL0018IL0017IL0015IL0024
ESP42895 ENT638_3715ENT638_3714ENT638_3712ENT638_3720ENT638_3716ENT638_3717ENT638_3718ENT638_3719ENT638_3721ENT638_3713
EFER585054 EFER_3267EFER_3266EFER_3272EFER_3268EFER_3269EFER_3270EFER_3271EFER_3273EFER_3265
ECOO157 YRDDYRDCYRDBSUNSMGSMFDEFFMTTRKAAROE
ECOL83334 ECS4149ECS4148ECS4146ECS4154ECS4150ECS4151ECS4152ECS4153ECS4155ECS4147
ECOL585397 ECED1_3947ECED1_3946ECED1_3944ECED1_3952ECED1_3948ECED1_3949ECED1_3950ECED1_3951ECED1_3953ECED1_3945
ECOL585056 ECUMN_3757ECUMN_3756ECUMN_3754ECUMN_3762ECUMN_3758ECUMN_3759ECUMN_3760ECUMN_3761ECUMN_3763ECUMN_3755
ECOL585055 EC55989_3700EC55989_3699EC55989_3697EC55989_3705EC55989_3701EC55989_3702EC55989_3703EC55989_3704EC55989_3706EC55989_3698
ECOL585035 ECS88_3671ECS88_3670ECS88_3668ECS88_3676ECS88_3672ECS88_3673ECS88_3674ECS88_3675ECS88_3677ECS88_3669
ECOL585034 ECIAI1_3433ECIAI1_3432ECIAI1_3430ECIAI1_3438ECIAI1_3434ECIAI1_3435ECIAI1_3436ECIAI1_3437ECIAI1_3439ECIAI1_3431
ECOL481805 ECOLC_0430ECOLC_0431ECOLC_0433ECOLC_0425ECOLC_0429ECOLC_0428ECOLC_0427ECOLC_0426ECOLC_0424ECOLC_0432
ECOL469008 ECBD_0468ECBD_0469ECBD_0471ECBD_0463ECBD_0467ECBD_0466ECBD_0465ECBD_0464ECBD_0462ECBD_0470
ECOL439855 ECSMS35_3579ECSMS35_3578ECSMS35_3575ECSMS35_3584ECSMS35_3580ECSMS35_3581ECSMS35_3582ECSMS35_3583ECSMS35_3585ECSMS35_3577
ECOL413997 ECB_03134ECB_03133ECB_03131ECB_03139ECB_03135ECB_03136ECB_03137ECB_03138ECB_03140ECB_03132
ECOL409438 ECSE_3558ECSE_3557ECSE_3555ECSE_3563ECSE_3559ECSE_3560ECSE_3561ECSE_3562ECSE_3564ECSE_3556
ECOL405955 APECO1_3163APECO1_3164APECO1_3158APECO1_3162APECO1_3161APECO1_3160APECO1_3159APECO1_3157APECO1_3165
ECOL364106 UTI89_C3728UTI89_C3727UTI89_C3725UTI89_C3733UTI89_C3729UTI89_C3730UTI89_C3731UTI89_C3732UTI89_C3734UTI89_C3726
ECOL362663 ECP_3371ECP_3370ECP_3368ECP_3376ECP_3372ECP_3373ECP_3374ECP_3375ECP_3377ECP_3369
ECOL331111 ECE24377A_3766ECE24377A_3765ECE24377A_3762ECE24377A_3771ECE24377A_3767ECE24377A_3768ECE24377A_3769ECE24377A_3770ECE24377A_3772ECE24377A_3764
ECOL316407 ECK3270:JW5949:B3283ECK3269:JW3243:B3282ECK3267:JW3241:B3280ECK3275:JW3250:B3289ECK3271:JW3245:B3284ECK3272:JW5708:B4473ECK3273:JW3248:B3287ECK3274:JW3249:B3288ECK3276:JW3251:B3290ECK3268:JW3242:B3281
ECOL199310 C4044C4043C4041C4049C4045C4046C4047C4048C4050C4042
ECAR218491 ECA3996ECA3996ECA3994ECA4001ECA3997ECA3998ECA3999ECA4000ECA4002ECA3995
CPSY167879 CPS_0024CPS_0027CPS_0018CPS_0023CPS_0022CPS_0020CPS_0019CPS_0017CPS_0030
ASAL382245 ASA_4136ASA_4134ASA_4131ASA_4142ASA_4137ASA_4138ASA_4140ASA_4141ASA_4143ASA_4132
AHYD196024 AHA_0262AHA_0264AHA_0267AHA_0256AHA_0261AHA_0260AHA_0258AHA_0257AHA_0255AHA_0266


Organism features enriched in list (features available for 72 out of the 75 orgs in the list)
Feature    Pvalue       Num occurrences in list  Total num occurrences  
Arrangment:Chains 0.0002091292
Arrangment:Pairs 1.935e-833112
Arrangment:Singles 0.009297544286
Disease:Bubonic_plague 2.940e-666
Disease:Dysentery 2.940e-666
Disease:Gastroenteritis 9.397e-81013
Disease:Meningitis_and_septicemia 0.000215944
GC_Content_Range4:0-40 4.617e-132213
GC_Content_Range4:40-60 2.311e-2869224
GC_Content_Range4:60-100 6.521e-91145
GC_Content_Range7:30-40 2.791e-92166
GC_Content_Range7:40-50 0.000013229117
GC_Content_Range7:50-60 1.152e-1440107
GC_Content_Range7:60-70 4.097e-81134
Genome_Size_Range5:2-4 2.332e-68197
Genome_Size_Range5:4-6 3.963e-2663184
Genome_Size_Range9:2-3 0.00193536120
Genome_Size_Range9:3-4 0.0014110277
Genome_Size_Range9:4-5 1.704e-103396
Genome_Size_Range9:5-6 2.332e-93088
Gram_Stain:Gram_Neg 5.132e-1871333
Motility:No 3.434e-82151
Motility:Yes 2.424e-753267
Optimal_temp.:20-30 0.005192047
Optimal_temp.:28-30 0.005192047
Oxygen_Req:Aerobic 0.00004459185
Oxygen_Req:Anaerobic 6.237e-61102
Oxygen_Req:Facultative 5.621e-2161201
Pathogenic_in:Human 3.672e-644213
Pathogenic_in:No 2.992e-611226
Pathogenic_in:Rodent 0.005192047
Shape:Rod 3.258e-863347
Temp._range:Psychrophilic 0.000171469



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ORGANISMS CONTAINING AT MOST 1 GENES FROM THE GROUP:

Total number of orgs: 96
Effective number of orgs (counting one per cluster within 468 clusters): 78

Organism list
Homologs in each organism in the list
Features enriched in organism list


Follow (ncbi) link, when present, to find the set of organism features for each organism
Org ID  Org Name  # genes in group found in org  
WPIP80849 Wolbachia endosymbiont of Brugia malayi1
UURE95667 Ureaplasma urealyticum serovar 131
UURE95664 Ureaplasma urealyticum serovar 101
UPAR505682 ncbi Ureaplasma parvum serovar 3 str. ATCC 278151
TWHI218496 ncbi Tropheryma whipplei TW08/270
TWHI203267 ncbi Tropheryma whipplei Twist0
TVOL273116 ncbi Thermoplasma volcanium GSS11
TACI273075 ncbi Thermoplasma acidophilum DSM 17281
STOK273063 ncbi Sulfolobus tokodaii 71
SSP84588 ncbi Synechococcus sp. WH 81021
SSP64471 ncbi Synechococcus sp. CC93111
SSOL273057 ncbi Sulfolobus solfataricus P21
SERY405948 ncbi Saccharopolyspora erythraea NRRL 23381
SACI330779 ncbi Sulfolobus acidocaldarius DSM 6391
RTYP257363 ncbi Rickettsia typhi Wilmington1
RRIC392021 ncbi Rickettsia rickettsii Sheila Smith1
RMAS416276 ncbi Rickettsia massiliae MTU51
RAKA293614 ncbi Rickettsia akari Hartford1
PTOR263820 ncbi Picrophilus torridus DSM 97901
PMAR74547 ncbi Prochlorococcus marinus MIT 93131
PISL384616 ncbi Pyrobaculum islandicum DSM 41841
PAST100379 Onion yellows phytoplasma1
PARS340102 ncbi Pyrobaculum arsenaticum DSM 135140
PAER178306 ncbi Pyrobaculum aerophilum IM20
PACN267747 ncbi Propionibacterium acnes KPA1712021
NSEN222891 ncbi Neorickettsia sennetsu Miyayama0
MVAN350058 ncbi Mycobacterium vanbaalenii PYR-11
MTUB419947 ncbi Mycobacterium tuberculosis H37Ra1
MTUB336982 ncbi Mycobacterium tuberculosis F111
MTBRV ncbi Mycobacterium tuberculosis H37Rv1
MTBCDC ncbi Mycobacterium tuberculosis CDC15511
MSYN262723 ncbi Mycoplasma synoviae 530
MSTA339860 ncbi Methanosphaera stadtmanae DSM 30911
MSP189918 ncbi Mycobacterium sp. KMS1
MSP164757 ncbi Mycobacterium sp. JLS1
MSP164756 ncbi Mycobacterium sp. MCS1
MSME246196 ncbi Mycobacterium smegmatis MC2 1551
MSED399549 ncbi Metallosphaera sedula DSM 53481
MPUL272635 ncbi Mycoplasma pulmonis UAB CTIP0
MPNE272634 ncbi Mycoplasma pneumoniae M1291
MPEN272633 ncbi Mycoplasma penetrans HF-21
MMYC272632 ncbi Mycoplasma mycoides mycoides SC str. PG10
MMOB267748 ncbi Mycoplasma mobile 163K0
MLEP272631 ncbi Mycobacterium leprae TN0
MHYO295358 ncbi Mycoplasma hyopneumoniae 2320
MHYO262722 ncbi Mycoplasma hyopneumoniae 74480
MHYO262719 ncbi Mycoplasma hyopneumoniae J0
MGEN243273 ncbi Mycoplasma genitalium G371
MFLO265311 ncbi Mesoplasma florum L10
MCAP340047 ncbi Mycoplasma capricolum capricolum ATCC 273430
MBOV410289 ncbi Mycobacterium bovis BCG str. Pasteur 1173P21
MBOV233413 ncbi Mycobacterium bovis AF2122/971
MAVI243243 ncbi Mycobacterium avium 1041
MART243272 ncbi Mycoplasma arthritidis 158L3-10
MABS561007 ncbi Mycobacterium abscessus ATCC 199771
LXYL281090 ncbi Leifsonia xyli xyli CTCB070
LBOR355277 ncbi Leptospira borgpetersenii serovar Hardjo-bovis JB1970
LBOR355276 ncbi Leptospira borgpetersenii serovar Hardjo-bovis L5500
LBIF456481 ncbi Leptospira biflexa serovar Patoc strain Patoc 1 (Paris)1
LBIF355278 ncbi Leptospira biflexa serovar Patoc strain Patoc 1 (Ames)1
FSP1855 Frankia sp. EAN1pec1
FJOH376686 ncbi Flavobacterium johnsoniae UW1011
CTRA471473 ncbi Chlamydia trachomatis L2b/UCH-1/proctitis1
CTRA471472 ncbi Chlamydia trachomatis 434/Bu1
CSUL444179 ncbi Candidatus Sulcia muelleri GWSS0
CPNE182082 ncbi Chlamydophila pneumoniae TW-1831
CPNE138677 ncbi Chlamydophila pneumoniae J1381
CPNE115713 ncbi Chlamydophila pneumoniae CWL0291
CPNE115711 ncbi Chlamydophila pneumoniae AR391
CMUR243161 ncbi Chlamydia muridarum Nigg1
CMIC443906 ncbi Clavibacter michiganensis michiganensis NCPPB 3820
CMIC31964 ncbi Clavibacter michiganensis sepedonicus0
CMAQ397948 ncbi Caldivirga maquilingensis IC-1671
CJEJ407148 ncbi Campylobacter jejuni jejuni 811161
CJEJ360109 ncbi Campylobacter jejuni doylei 269.971
CJEJ192222 ncbi Campylobacter jejuni jejuni NCTC 111681
CJEI306537 ncbi Corynebacterium jeikeium K4110
CGLU196627 ncbi Corynebacterium glutamicum ATCC 130321
CFEL264202 ncbi Chlamydophila felis Fe/C-561
CCAV227941 ncbi Chlamydophila caviae GPIC1
CABO218497 ncbi Chlamydophila abortus S26/31
BXEN266265 ncbi Burkholderia xenovorans LB4000
BTUR314724 ncbi Borrelia turicatae 91E1351
BLON206672 ncbi Bifidobacterium longum NCC27051
BHER314723 ncbi Borrelia hermsii DAH0
BGAR290434 ncbi Borrelia garinii PBi0
BBUR224326 ncbi Borrelia burgdorferi B310
BAFZ390236 ncbi Borrelia afzelii PKo0
AYEL322098 ncbi Aster yellows witches-broom phytoplasma AYWB1
AURANTIMONAS Aurantimonas manganoxydans SI85-9A10
ASP1667 Arthrobacter sp.1
APER272557 ncbi Aeropyrum pernix K11
ANAE240017 Actinomyces oris MG11
ALAI441768 ncbi Acholeplasma laidlawii PG-8A1
ACEL351607 ncbi Acidothermus cellulolyticus 11B1
AAUR290340 ncbi Arthrobacter aurescens TC11


Names of the homologs of the genes in the group in each of these orgs
  G7699   G7698   G7697   EG12163   EG11605   EG11604   EG11440   EG11268   EG11019   EG10077   
WPIP80849 WB_0187
UURE95667 UU590
UURE95664 UUR10_0695
UPAR505682 UPA3_0630
TWHI218496
TWHI203267
TVOL273116 TVN0019
TACI273075 TA0063
STOK273063 ST1526
SSP84588 SYNW1679OR3038
SSP64471 GSYN0731
SSOL273057 SSO0664
SERY405948 SACE_1811
SACI330779 SACI_1642
RTYP257363 RT0197
RRIC392021 A1G_01595
RMAS416276 RMA_0279
RAKA293614 A1C_01560
PTOR263820 PTO0747
PMAR74547 PMT0270
PISL384616 PISL_0378
PAST100379 PAM279
PARS340102
PAER178306
PACN267747 PPA1058
NSEN222891
MVAN350058 MVAN_2473
MTUB419947 MRA_2720
MTUB336982 TBFG_12707
MTBRV RV2692
MTBCDC MT2766
MSYN262723
MSTA339860 MSP_0250
MSP189918 MKMS_2242
MSP164757 MJLS_2185
MSP164756 MMCS_2196
MSME246196 MSMEG_2769
MSED399549 MSED_2011
MPUL272635
MPNE272634 MPN261
MPEN272633 MYPE4140
MMYC272632
MMOB267748
MLEP272631
MHYO295358
MHYO262722
MHYO262719
MGEN243273 MG_122
MFLO265311
MCAP340047
MBOV410289 BCG_2705
MBOV233413 MB2711
MAVI243243 MAV_3583
MART243272
MABS561007 MAB_2995
LXYL281090
LBOR355277
LBOR355276
LBIF456481 LEPBI_I1839
LBIF355278 LBF_1786
FSP1855 FRANEAN1_5192
FJOH376686 FJOH_3691
CTRA471473 CTLON_0011
CTRA471472 CTL0011
CSUL444179
CPNE182082 CPB0796
CPNE138677 CPJ0769
CPNE115713 CPN0769
CPNE115711 CP_1103
CMUR243161 TC_0012
CMIC443906
CMIC31964
CMAQ397948 CMAQ_0281
CJEJ407148 C8J_1583
CJEJ360109 JJD26997_2058
CJEJ192222 CJ1686C
CJEI306537
CGLU196627 CG1802
CFEL264202 CF0025
CCAV227941 CCA_00988
CABO218497 CAB958
BXEN266265
BTUR314724 BT0734
BLON206672 BL1789
BHER314723
BGAR290434
BBUR224326
BAFZ390236
AYEL322098 AYWB_442
AURANTIMONAS
ASP1667 ARTH_1640
APER272557 APE2397
ANAE240017 ANA_0621
ALAI441768 ACL_0339
ACEL351607 ACEL_1398
AAUR290340 AAUR_1784


Organism features enriched in list (features available for 88 out of the 96 orgs in the list)
Feature    Pvalue       Num occurrences in list  Total num occurrences  
Arrangment:Chains 0.0014341592
Arrangment:Pairs 0.00008895112
Disease:Pharyngitis 2.038e-788
Disease:Tuberculosis 0.003339933
Disease:bronchitis_and_pneumonitis 2.038e-788
Endospores:No 2.672e-1160211
Endospores:Yes 0.0058577253
GC_Content_Range7:0-30 1.397e-62047
Genome_Size_Range5:0-2 8.361e-1048155
Genome_Size_Range5:4-6 5.991e-611184
Genome_Size_Range9:0-1 8.405e-142127
Genome_Size_Range9:4-5 0.0026350696
Genome_Size_Range9:5-6 0.0023863588
Gram_Stain:Gram_Neg 0.003024739333
Habitat:Aquatic 0.0047336691
Habitat:Host-associated 1.464e-651206
Habitat:Multiple 0.000917515178
Motility:No 0.000059438151
Motility:Yes 0.000734527267
Optimal_temp.:37 1.493e-633106
Oxygen_Req:Aerobic 0.002525939185
Oxygen_Req:Anaerobic 0.00037415102
Oxygen_Req:Facultative 0.003777220201
Pathogenic_in:No 0.001352622226
Salinity:Non-halophilic 0.000046730106
Shape:Sphere 1.349e-111619
Shape:Spiral 0.00158851234



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ORGANISMS ENRICHED FOR GROUP:




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ORGANISMS DEPLETED FOR GROUP:




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PHYLOGENETIC PROFILE SIMILARITY WITH KNOWN PATHWAYS:

Pathways or complexes with absolute value of Pearson coefficient with respect to candidate larger than 0.4 are listed below
The candidate is assumed to exist in orgs listed in section List of organisms containing most genes from the group


Pathway or complex  # Orgs containing it  # of those orgs also containing candidate  Pearson Coeff  
GALACTITOLCAT-PWY (galactitol degradation)73470.5860
PWY-5861 (superpathway of demethylmenaquinone-8 biosynthesis)50370.5625
PWY0-1315 (L-lactaldehyde degradation (anaerobic))45330.5256
AST-PWY (arginine degradation II (AST pathway))120560.5198
PWY0-1241 (ADP-L-glycero-β-D-manno-heptose biosynthesis)218740.4939
HEXITOLDEGSUPER-PWY (superpathway of hexitol degradation)37270.4705
TREDEGLOW-PWY (trehalose degradation I (low osmolarity))121520.4667
PWY0-1355 (formate to trimethylamine N-oxide electron transfer)31240.4598
SORBDEG-PWY (sorbitol degradation II)53320.4530
LYXMET-PWY (L-lyxose degradation)87420.4486
GLYCOCAT-PWY (glycogen degradation I)246740.4479
RHAMCAT-PWY (rhamnose degradation)91430.4476
LIPA-CORESYN-PWY (Lipid A-core biosynthesis)176620.4471
PWY-46 (putrescine biosynthesis III)138540.4441
THREONINE-DEG2-PWY (threonine degradation II)214680.4387
PWY0-1356 (formate to dimethyl sulfoxide electron transfer)22190.4370
LPSSYN-PWY (superpathway of lipopolysaccharide biosynthesis)91420.4336
GLUTDEG-PWY (glutamate degradation II)194640.4330
MANNIDEG-PWY (mannitol degradation I)99440.4329
ECASYN-PWY (enterobacterial common antigen biosynthesis)191630.4280
GLUCONSUPER-PWY (D-gluconate degradation)229690.4239
ENTNER-DOUDOROFF-PWY (Entner-Doudoroff pathway I)249720.4232
GLYCOLYSIS-E-D (superpathway of glycolysis and Entner-Doudoroff)249720.4232
COBALSYN-PWY (adenosylcobalamin salvage from cobinamide I)195630.4204
ARABCAT-PWY (L-arabinose degradation I)128490.4101
PWY-5833 (CDP-3,6-dideoxyhexose biosynthesis)14140.4098
PWY-5148 (acyl-CoA hydrolysis)227670.4066
KDOSYN-PWY (KDO transfer to lipid IVA I)180590.4063
PWY-5921 (L-glutamine biosynthesis II (tRNA-dependent))4016-.4354



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PAIRWISE GENOME CONTEXT SCORE MATRIX:

  G7698   G7697   EG12163   EG11605   EG11604   EG11440   EG11268   EG11019   EG10077   
G76990.9991180.9988480.9993120.9994660.9998860.9993730.9993610.9986860.999082
G76980.9989920.9991610.9993640.999360.9993360.9992880.9990990.999485
G76970.9986270.9987730.9987390.9987140.9986710.9985880.999152
EG121630.9994330.999660.9998490.9999450.9995980.999168
EG116050.9996680.9995760.9995490.9991540.999093
EG116040.9997880.9997450.9993410.998985
EG114400.9999890.9994590.999211
EG112680.9995130.999133
EG110190.998904
EG10077



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PAIRWISE BLAST SCORES:

  G7699   G7698   G7697   EG12163   EG11605   EG11604   EG11440   EG11268   EG11019   EG10077   
G76990.0f0---------
G7698-0.0f0--------
G7697--0.0f0-------
EG12163---0.0f0------
EG11605----0.0f0-----
EG11604-----0.0f0----
EG11440------0.0f0---
EG11268-------0.0f0--
EG11019--------0.0f0-
EG10077---------0.0f0



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PATHWAYS OR PROTEIN COMPLEX MATCHES IN TARGET ORG:

For each case, all genes involved in the pathway or complex are listed. For each gene we list: a tag indicating whether the gene is part of the candidate list or not, the average and the minimum scores of the gene to the candidate list, the gene name, and its product names.



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GENOME CONTEXT INFORMATION:

Each row corresponds to a replicon in an organism, each column to a gene in the candidate. The second column indicates whether the organims was included in the list used to compute the genome context scores or not. Some organisms are not included because they are phylogenetically too similar to others already in the list.
The number in the matrix indicate the position of the homolog of the gene in the replicon. All numbers are relative to the smaller one, which is assigned a position of zero. Two columns with the same number indicate that the two genes matched the same gene in that organism.

Genome browser links for gene clusters

The links below opens a genome browser BioCyc page for each cluster of genes in the target genome. These pages shows the central gene of the cluster in the target genome and its best homolog in the reference genomes, for the genomes that contain homologs for at least 75% of the genes in the group. Only one genome per phylogenetic cluster of organisms is shown, to keep the list smaller.

EG10077 EG11019 EG11268 EG11440 EG11604 EG11605 EG12163 G7697 G7698 G7699 (centered at EG11604)


ORG:REPLICON:CIRC?\GENE  IN REF LIST  G7699   G7698   G7697   EG12163   EG11605   EG11604   EG11440   EG11268   EG11019   EG10077   
311/623354/62352/623396/623119/623411/623378/623410/623308/623408/623
AAEO224324:0:Tyes------01087-214
AAUR290340:2:Tyes--------0-
AAVE397945:0:Tyes---3626-37823784378636420
ABAC204669:0:Tyes7330-1632-73416921631--
ABAU360910:0:Tyes---303190045342814
ABOR393595:0:Tyes-6-1-53208
ABUT367737:0:Tyes------625--0
ACAU438753:0:Tyes---4760-288080480331150
ACEL351607:0:Tyes--------0-
ACRY349163:8:Tyes---2253-32001-2362
ADEH290397:0:Tyes19961745---199703278--
AEHR187272:0:Tyes-11-498650203
AFER243159:0:Tyes21470-21412146214521432142-1984
AFUL224325:0:Tyes10150------571528
AHYD196024:0:Tyes791216532011
ALAI441768:0:Tyes0---------
AMAR234826:0:Tyes-72---0654---
AMAR329726:9:Tyes-469-941-0----
AMET293826:0:Tyes23490-2395-2350239923984038729
ANAE240017:0:Tyes--------0-
AORE350688:0:Tyes14312602-1388-1430138413856410
APER272557:0:Tyes-0--------
APHA212042:0:Tyes-0---147545---
APLE416269:0:Tyes-1-450-6086074784490
APLE434271:0:Tno21-462-6246234954610
ASAL382245:5:Tyes5301167910121
ASP1667:3:Tyes--------0-
ASP232721:2:Tyes---241-4034054072670
ASP62928:0:Tyes-1317-395101343947617
ASP62977:0:Tyes-0-3177-133176-196
ASP76114:2:Tyes---6567337327307296520
AVAR240292:3:Tyes---3607-29710-239-
AYEL322098:4:Tyes0---------
BABO262698:0:Tno-----0326325--
BABO262698:1:Tno---665----0906
BAMB339670:3:Tno---2720-272527242723-0
BAMB398577:3:Tno---2552-255725562555-0
BAMY326423:0:Tyes401854-2-3901-840
BANT260799:0:Tno01507-32--3433-546
BANT261594:2:Tno01513-31--3332-568
BANT568206:2:Tyes344863-2--01-3886
BANT592021:2:Tno01551-32--3433-573
BAPH198804:0:Tyes-1--2-34-0
BAPH372461:0:Tyes------1--0
BBAC264462:0:Tyes-0----22282227--
BBAC360095:0:Tyes---0-72111611162450-
BBRO257310:0:Tyes---184761034224198
BCAN483179:0:Tno-----0423422--
BCAN483179:1:Tno---687----0947
BCEN331271:2:Tno---2405-241024092408-0
BCEN331272:3:Tyes---2505-251025092508-0
BCER226900:1:Tyes01463-32-13433-492
BCER288681:0:Tno01449-32-13433-486
BCER315749:1:Tyes01312-32-13433-565
BCER405917:1:Tyes01514-32-13533-521
BCER572264:1:Tno01492-32-13433-501
BCIC186490:0:Tyes-2----10-3
BCLA66692:0:Tyes6452244-684-646-6857930
BFRA272559:1:Tyes-2820-----28180-
BFRA295405:0:Tno-3070-----30680-
BHAL272558:0:Tyes11472466-1187-1148-1188-0
BHEN283166:0:Tyes---1468-76564635530
BJAP224911:0:Fyes---0-455675797578-5853
BLIC279010:0:Tyes392075-2-3801-941
BLON206672:0:Tyes-------0--
BMAL243160:1:Tno---5-012-2102
BMAL320388:1:Tno---2333-234023382337-0
BMAL320389:1:Tyes---7-023-926
BMEL224914:0:Tno-----40901--
BMEL224914:1:Tno---0----6501858
BMEL359391:0:Tno-----0323322--
BMEL359391:1:Tno---639----0869
BOVI236:0:Tyes-----0351350--
BOVI236:1:Tyes---597----0809
BPAR257311:0:Tno---193956034233530
BPER257313:0:Tyes---10108885841052298
BPET94624:0:Tyes-3599-472304740473947384719531
BPSE272560:1:Tyes---5-012-2873
BPSE320372:1:Tno---8-023-3277
BPSE320373:1:Tno---5--01-3193
BPUM315750:0:Tyes391869-2-3801-818
BQUI283165:0:Tyes-----57161604550
BSP107806:2:Tyes-1--2-34-0
BSP36773:2:Tyes---2824-282928282827-0
BSP376:0:Tyes3957--0-3955395396-1884
BSUB:0:Tyes412214-2-4001-1032
BSUI204722:0:Tyes-----0408407--
BSUI204722:1:Tyes---675----0920
BSUI470137:0:Tno---655-0400399--
BSUI470137:1:Tno---------0
BTHA271848:1:Tno---5-012-1033
BTHE226186:0:Tyes-3598---2713036003755-
BTHU281309:1:Tno01424-32-13433-494
BTHU412694:1:Tno01330-32-13433-446
BTRI382640:1:Tyes---2018-100067667700
BTUR314724:0:Fyes-0--------
BVIE269482:7:Tyes---2673-267826772676-0
BWEI315730:4:Tyes01471-32-13433-520
CABO218497:0:Tyes0---------
CACE272562:1:Tyes883--824-882821822-0
CAULO:0:Tyes-3433-100-2481271278-0
CBEI290402:0:Tyes41--3-4001--
CBLO203907:0:Tyes-2----10-3
CBLO291272:0:Tno-2----10-3
CBOT36826:1:Tno22640-2331-2265233423331153-
CBOT441770:0:Tyes20750-2147-2076215021491133-
CBOT441771:0:Tno20460-2117-204721202119--
CBOT441772:1:Tno22350-2303-2236230623051175-
CBOT498213:1:Tno22120-2283-2213228622851183-
CBOT508765:1:Tyes7540-716-753713714--
CBOT515621:2:Tyes24250-2500-2426250325021215-
CBOT536232:0:Tno24540-2527-2455253025291249-
CBUR227377:1:Tyes19141917-1831191319129391911-0
CBUR360115:1:Tno30-1926458147-1999
CBUR434922:2:Tno18791882-68187818778771875-0
CCAV227941:1:Tyes0---------
CCHL340177:0:Tyes01504-1049-1380----
CCON360104:2:Tyes1769-----0--1595
CCUR360105:0:Tyes1623-----0--373
CDES477974:0:Tyes3091849-1294-308-12950679
CDIF272563:1:Tyes12237-1330-013341333--
CDIP257309:0:Tyes-0-279------
CEFF196164:0:Fyes-0-424------
CFEL264202:1:Tyes0---------
CFET360106:0:Tyes0-----1474--941
CGLU196627:0:Tyes---0------
CHOM360107:1:Tyes1499-----0--1589
CHUT269798:0:Tyes------0861--
CHYD246194:0:Tyes11391879-838-1140841840-0
CJAP155077:0:Tyes-7-1-53209
CJEJ192222:0:Tyes0---------
CJEJ195099:0:Tno1351--------0
CJEJ354242:2:Tyes1198--------0
CJEJ360109:0:Tyes0---------
CJEJ407148:0:Tno0---------
CKLU431943:1:Tyes462302-3-4501--
CKOR374847:0:Tyes-417-------0
CMAQ397948:0:Tyes-0--------
CMET456442:0:Tyes-31------0-
CMUR243161:1:Tyes0---------
CNOV386415:0:Tyes0--91-19493--
CPEL335992:0:Tyes------117-6100
CPER195102:1:Tyes1003--1042-100410451044-0
CPER195103:0:Tno1246--1284-124712871286-0
CPER289380:3:Tyes970--1008-97110111010-0
CPHY357809:0:Tyes2311246---23210--
CPNE115711:1:Tyes0---------
CPNE115713:0:Tno0---------
CPNE138677:0:Tno0---------
CPNE182082:0:Tno0---------
CPRO264201:0:Fyes0----1-341--
CPSY167879:0:Tyes710-16532013
CRUT413404:0:Tyes-264-0774-703530142207
CSAL290398:0:Tyes-2-7-356100
CSP501479:7:Fyes-220-------0
CSP501479:8:Fyes-----88618101290-
CSP78:2:Tyes---3304-030943092-3539
CTEP194439:0:Tyes0--543-199----
CTET212717:0:Tyes94263-907-9419049050-
CTRA471472:0:Tyes0---------
CTRA471473:0:Tno0---------
CVES412965:0:Tyes-109--571-508362059
CVIO243365:0:Tyes38310-38243830382938273826-3123
DARO159087:0:Tyes---9-023-3923
DDES207559:0:Tyes952311---15880120493607
DETH243164:0:Tyes673777---67470815490424
DGEO319795:1:Tyes-----1070---0
DHAF138119:0:Tyes8063194-944-8079469450646
DNOD246195:0:Tyes-184-50134-346
DOLE96561:0:Tyes5660-350-5653523511351-
DPSY177439:2:Tyes-2121-0-6936456466122964
DRAD243230:3:Tyes-----0---1037
DRED349161:0:Tyes9632165-694-96469169219040
DSHI398580:5:Tyes---2894-9780214133313
DSP216389:0:Tyes625740---62666713920414
DSP255470:0:Tno538675---53960114780328
DVUL882:1:Tyes32571134---194232343233-0
ECAN269484:0:Tyes-243---1840---
ECAR218491:0:Tyes2207345681
ECHA205920:0:Tyes-0---78----
ECOL199310:0:Tno3208456791
ECOL316407:0:Tno6791543208
ECOL331111:6:Tno3208456791
ECOL362663:0:Tno3208456791
ECOL364106:1:Tno3208456791
ECOL405955:2:Tyes21-7345680
ECOL409438:6:Tyes3208456791
ECOL413997:0:Tno3208456791
ECOL439855:4:Tno3208456791
ECOL469008:0:Tno6791543208
ECOL481805:0:Tno6791543208
ECOL585034:0:Tno3208456791
ECOL585035:0:Tno3208456791
ECOL585055:0:Tno3208456791
ECOL585056:2:Tno3208456791
ECOL585057:0:Tno21-63-4570
ECOL585397:0:Tno3208456791
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