CANDIDATE ID: 656

CANDIDATE ID: 656

NUMBER OF GENES: 5
AVERAGE SCORE:    9.9928570e-1 (range=[0.0,1.0])
AVERAGE MINIMUM BLAST P-VAL:    1.0000000e+0

Gene List
List of organisms containing most genes from the group
    Phylogenetic tree highlighting these organisms (opens new page)
List of organisms containing very few or no genes from the group
List of organisms enriched for group
List of organisms depleted for group
Phylogenetic profile similarity with known pathways
Pairwise genome context scores
Pairwise Blast scores
Pathway or protein complex matches in target organism
Genome context matrix
    Genes and their orthologs in genome browser BioCyc pages



GENE LIST:

- EG12878 (zapA) (b2910)
   Products of gene:
     - EG12878-MONOMER (protein that localizes to the cytokinetic ring)
     - CPLX0-7538 (protein that localizes to the cytokinetic ring)

- EG11810 (gcvP) (b2903)
   Products of gene:
     - GCVP-MONOMER (glycine decarboxylase)
     - GCVP-CPLX (glycine decarboxylase)
       Reactions:
        H-Gcv-protein-(lipoyl)lysine + glycine  ->  H-protein-S-(aminomethyldihydrolipoyl)lysine + CO2
         In pathways
         GLYCLEAV-PWY (glycine cleavage complex)
     - GCVMULTI-CPLX (glycine cleavage system)
       Reactions:
        NAD+ + glycine + tetrahydrofolate + H+  ->  ammonia + CO2 + NADH + 5,10-methylene-THF
         In pathways
         GLYCINE-SYN2-PWY (GLYCINE-SYN2-PWY)
         PWY-2201 (PWY-2201)
         PWY-3841 (PWY-3841)
         1CMET2-PWY (formylTHF biosynthesis I)
         PWY-181 (PWY-181)

- EG11442 (gcvT) (b2905)
   Products of gene:
     - GCVT-MONOMER (aminomethyltransferase)
       Reactions:
        H-protein-S-(aminomethyldihydrolipoyl)lysine + tetrahydrofolate  ->  H-Gcv-protein-(dihydrolipoyl)lysine + ammonia + 5,10-methylene-THF
         In pathways
         GLYCLEAV-PWY (glycine cleavage complex)
     - GCVMULTI-CPLX (glycine cleavage system)
       Reactions:
        NAD+ + glycine + tetrahydrofolate + H+  ->  ammonia + CO2 + NADH + 5,10-methylene-THF
         In pathways
         GLYCINE-SYN2-PWY (GLYCINE-SYN2-PWY)
         PWY-2201 (PWY-2201)
         PWY-3841 (PWY-3841)
         1CMET2-PWY (formylTHF biosynthesis I)
         PWY-181 (PWY-181)

- EG11323 (ygfB) (b2909)
   Products of gene:
     - EG11323-MONOMER (predicted protein)

- EG10371 (gcvH) (b2904)
   Products of gene:
     - GCVH-MONOMER (glycine cleavage system H protein)
     - AMINOMETHYLDIHYDROLIPOYL-GCVH (H-protein-S-(aminomethyldihydrolipoyl)lysine)
     - DIHYDROLIPOYL-GCVH (H-Gcv-protein-(dihydrolipoyl)lysine)
     - LIPOYL-GCVH (lipoyl-GcvH-protein)
     - GCVMULTI-CPLX (glycine cleavage system)
       Reactions:
        NAD+ + glycine + tetrahydrofolate + H+  ->  ammonia + CO2 + NADH + 5,10-methylene-THF
         In pathways
         GLYCINE-SYN2-PWY (GLYCINE-SYN2-PWY)
         PWY-2201 (PWY-2201)
         PWY-3841 (PWY-3841)
         1CMET2-PWY (formylTHF biosynthesis I)
         PWY-181 (PWY-181)



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ORGANISMS CONTAINING AT LEAST 4 GENES FROM THE GROUP:

Total number of orgs: 136
Effective number of orgs (counting one per cluster within 468 clusters): 80

Organism list
Homologs in each organism in the list
Features enriched in organism list


Follow (ncbi) link, when present, to find the set of organism features for each organism
Org ID  Org Name  # genes in group found in org  
YPSE349747 ncbi Yersinia pseudotuberculosis IP 317585
YPSE273123 ncbi Yersinia pseudotuberculosis IP 329535
YPES386656 ncbi Yersinia pestis Pestoides F5
YPES377628 ncbi Yersinia pestis Nepal5165
YPES360102 ncbi Yersinia pestis Antiqua5
YPES349746 ncbi Yersinia pestis Angola5
YPES214092 ncbi Yersinia pestis CO925
YPES187410 ncbi Yersinia pestis KIM 105
YENT393305 ncbi Yersinia enterocolitica enterocolitica 80815
XORY360094 ncbi Xanthomonas oryzae pv. oryzae PXO99A5
XORY342109 ncbi Xanthomonas oryzae pv. oryzae MAFF 3110185
XORY291331 ncbi Xanthomonas oryzae pv. oryzae KACC103315
XFAS405440 ncbi Xylella fastidiosa M125
XFAS183190 ncbi Xylella fastidiosa Temecula15
XFAS160492 ncbi Xylella fastidiosa 9a5c5
XCAM487884 Xanthomonas campestris pv. paulliniae5
XCAM316273 ncbi Xanthomonas campestris pv. vesicatoria str. 85-105
XCAM314565 ncbi Xanthomonas campestris pv. campestris str. 80045
XCAM190485 ncbi Xanthomonas campestris pv. campestris str. ATCC 339135
XAXO190486 ncbi Xanthomonas axonopodis pv. citri str. 3065
VVUL216895 ncbi Vibrio vulnificus CMCP65
VVUL196600 ncbi Vibrio vulnificus YJ0165
VPAR223926 ncbi Vibrio parahaemolyticus RIMD 22106335
VFIS312309 ncbi Vibrio fischeri ES1145
VCHO345073 ncbi Vibrio cholerae O3955
TTUR377629 ncbi Teredinibacter turnerae T79015
TDEN292415 ncbi Thiobacillus denitrificans ATCC 252594
STYP99287 ncbi Salmonella enterica enterica serovar Typhimurium str. LT25
SSP94122 ncbi Shewanella sp. ANA-35
SSON300269 ncbi Shigella sonnei Ss0465
SSED425104 ncbi Shewanella sediminis HAW-EB35
SPRO399741 ncbi Serratia proteamaculans 5685
SPEA398579 ncbi Shewanella pealeana ATCC 7003455
SONE211586 ncbi Shewanella oneidensis MR-15
SLOI323850 ncbi Shewanella loihica PV-45
SHIGELLA ncbi Shigella flexneri 2a str. 2457T5
SHAL458817 ncbi Shewanella halifaxensis HAW-EB45
SGLO343509 ncbi Sodalis glossinidius morsitans5
SFLE373384 ncbi Shigella flexneri 5 str. 84015
SFLE198214 ncbi Shigella flexneri 2a str. 3015
SENT454169 ncbi Salmonella enterica enterica serovar Heidelberg str. SL4765
SENT321314 ncbi Salmonella enterica enterica serovar Choleraesuis str. SC-B675
SENT295319 ncbi Salmonella enterica enterica serovar Paratyphi A str. ATCC 91505
SENT220341 ncbi Salmonella enterica enterica serovar Typhi str. CT185
SENT209261 ncbi Salmonella enterica enterica serovar Typhi str. Ty25
SDYS300267 ncbi Shigella dysenteriae Sd1975
SDEN318161 ncbi Shewanella denitrificans OS2175
SDEG203122 ncbi Saccharophagus degradans 2-404
SBOY300268 ncbi Shigella boydii Sb2275
SBAL402882 ncbi Shewanella baltica OS1855
SBAL399599 ncbi Shewanella baltica OS1955
RPAL316058 ncbi Rhodopseudomonas palustris HaA24
RPAL316055 ncbi Rhodopseudomonas palustris BisA534
PSYR223283 ncbi Pseudomonas syringae pv. tomato str. DC30004
PSYR205918 ncbi Pseudomonas syringae pv. syringae B728a4
PSTU379731 ncbi Pseudomonas stutzeri A15014
PSP56811 Psychrobacter sp.5
PPUT76869 ncbi Pseudomonas putida GB-14
PPUT351746 ncbi Pseudomonas putida F15
PPUT160488 ncbi Pseudomonas putida KT24405
PPRO298386 ncbi Photobacterium profundum SS94
PMEN399739 ncbi Pseudomonas mendocina ymp5
PLUM243265 ncbi Photorhabdus luminescens laumondii TTO15
PING357804 ncbi Psychromonas ingrahamii 375
PHAL326442 ncbi Pseudoalteromonas haloplanktis TAC1255
PFLU220664 ncbi Pseudomonas fluorescens Pf-55
PFLU216595 ncbi Pseudomonas fluorescens SBW255
PFLU205922 ncbi Pseudomonas fluorescens Pf0-14
PENT384676 ncbi Pseudomonas entomophila L484
PCRY335284 ncbi Psychrobacter cryohalolentis K54
PATL342610 ncbi Pseudoalteromonas atlantica T6c4
PARC259536 ncbi Psychrobacter arcticus 273-44
PAER208964 ncbi Pseudomonas aeruginosa PAO15
PAER208963 ncbi Pseudomonas aeruginosa UCBPP-PA145
NOCE323261 ncbi Nitrosococcus oceani ATCC 197075
NMUL323848 ncbi Nitrosospira multiformis ATCC 251964
NMEN374833 ncbi Neisseria meningitidis 0534424
NMEN272831 ncbi Neisseria meningitidis FAM184
NMEN122587 ncbi Neisseria meningitidis Z24914
NGON242231 ncbi Neisseria gonorrhoeae FA 10904
NEUR228410 ncbi Nitrosomonas europaea ATCC 197184
MSP400668 ncbi Marinomonas sp. MWYL15
MCAP243233 ncbi Methylococcus capsulatus Bath5
LPNE400673 ncbi Legionella pneumophila Corby4
LPNE297246 ncbi Legionella pneumophila Paris4
LPNE297245 ncbi Legionella pneumophila Lens4
LPNE272624 ncbi Legionella pneumophila pneumophila Philadelphia 14
KPNE272620 ncbi Klebsiella pneumoniae pneumoniae MGH 785785
ILOI283942 ncbi Idiomarina loihiensis L2TR5
HHAL349124 ncbi Halorhodospira halophila SL15
HCHE349521 ncbi Hahella chejuensis KCTC 23965
FTUL458234 ncbi Francisella tularensis holarctica FTNF002-004
FTUL418136 ncbi Francisella tularensis tularensis WY96-34184
FTUL401614 ncbi Francisella novicida U1124
FTUL393115 ncbi Francisella tularensis tularensis FSC1984
FTUL393011 ncbi Francisella tularensis holarctica OSU184
FTUL351581 Francisella tularensis holarctica FSC2004
FRANT ncbi Francisella tularensis tularensis SCHU S44
FPHI484022 ncbi Francisella philomiragia philomiragia ATCC 250174
ESP42895 Enterobacter sp.5
EFER585054 ncbi Escherichia fergusonii ATCC 354695
ECOO157 ncbi Escherichia coli O157:H7 EDL9335
ECOL83334 Escherichia coli O157:H75
ECOL585397 ncbi Escherichia coli ED1a5
ECOL585057 ncbi Escherichia coli IAI395
ECOL585056 ncbi Escherichia coli UMN0265
ECOL585055 ncbi Escherichia coli 559895
ECOL585035 ncbi Escherichia coli S885
ECOL585034 ncbi Escherichia coli IAI15
ECOL481805 ncbi Escherichia coli ATCC 87395
ECOL469008 ncbi Escherichia coli BL21(DE3)5
ECOL439855 ncbi Escherichia coli SMS-3-55
ECOL413997 ncbi Escherichia coli B str. REL6065
ECOL409438 ncbi Escherichia coli SE115
ECOL405955 ncbi Escherichia coli APEC O15
ECOL364106 ncbi Escherichia coli UTI895
ECOL362663 ncbi Escherichia coli 5365
ECOL331111 ncbi Escherichia coli E24377A5
ECOL316407 ncbi Escherichia coli K-12 substr. W31105
ECOL199310 ncbi Escherichia coli CFT0735
ECAR218491 ncbi Pectobacterium atrosepticum SCRI10435
DNOD246195 ncbi Dichelobacter nodosus VCS1703A5
DARO159087 ncbi Dechloromonas aromatica RCB4
CVIO243365 ncbi Chromobacterium violaceum ATCC 124724
CSAL290398 ncbi Chromohalobacter salexigens DSM 30434
CPSY167879 ncbi Colwellia psychrerythraea 34H5
CJAP155077 Cellvibrio japonicus5
CBUR434922 ncbi Coxiella burnetii Dugway 5J108-1114
CBUR360115 ncbi Coxiella burnetii RSA 3314
CBUR227377 ncbi Coxiella burnetii RSA 4934
ASP62928 ncbi Azoarcus sp. BH724
ASAL382245 ncbi Aeromonas salmonicida salmonicida A4495
AHYD196024 Aeromonas hydrophila dhakensis5
AEHR187272 ncbi Alkalilimnicola ehrlichii MLHE-15
ABOR393595 ncbi Alcanivorax borkumensis SK24
AAVE397945 ncbi Acidovorax citrulli AAC00-14


Names of the homologs of the genes in the group in each of these orgs
  EG12878   EG11810   EG11442   EG11323   EG10371   
YPSE349747 YPSIP31758_0858YPSIP31758_0865YPSIP31758_0863YPSIP31758_0859YPSIP31758_0864
YPSE273123 YPTB3187YPTB3180YPTB3182YPTB3186YPTB3181
YPES386656 YPDSF_0602YPDSF_0609YPDSF_0607YPDSF_0603YPDSF_0608
YPES377628 YPN_3111YPN_3104YPN_3106YPN_3110YPN_3105
YPES360102 YPA_0355YPA_0362YPA_0360YPA_0356YPA_0361
YPES349746 YPANGOLA_A3825YPANGOLA_A3832YPANGOLA_A3830YPANGOLA_A3826YPANGOLA_A3831
YPES214092 YPO0912YPO0905YPO0907YPO0911YPO0906
YPES187410 Y3299Y3292Y3294Y3298Y3293
YENT393305 YE3398YE3391YE3393YE3397YE3392
XORY360094 XOOORF_4217XOOORF_1323XOOORF_3210XOOORF_4215XOOORF_3208
XORY342109 XOO1026XOO3351XOO1697XOO1028XOO1698
XORY291331 XOO1130XOO3547XOO1794XOO1132XOO1795
XFAS405440 XFASM12_0963XFASM12_0737XFASM12_0155XFASM12_0965XFASM12_0154
XFAS183190 PD_0800PD_0620PD_0149PD_0802PD_0148
XFAS160492 XF2012XF1385XF0183XF2010XF0181
XCAM487884 XCC-B100_0922XCC-B100_3229XCC-B100_1276XCC-B100_0924XCC-B100_1277
XCAM316273 XCAORF_3603XCAORF_1334XCAORF_3256XCAORF_3601XCAORF_3255
XCAM314565 XC_0902XC_3135XC_1232XC_0904XC_1233
XCAM190485 XCC3262XCC1112XCC2877XCC3260XCC2876
XAXO190486 XAC3408XAC1214XAC3061XAC3406XAC3060
VVUL216895 VV1_1549VV2_0186VV2_0190VV1_1551VV2_0187
VVUL196600 VV2848VVA0691VVA0696VV2847VVA0692
VPAR223926 VP2590VPA0801VPA0805VP2588VPA0802
VFIS312309 VF2103VFA0703VFA0700VF2102VFA0702
VCHO345073 VC0395_A2054VC0395_0955VC0395_0949VC0395_A2053VC0395_0953
TTUR377629 TERTU_0398TERTU_0724TERTU_0356TERTU_0401TERTU_0357
TDEN292415 TBD_2723TBD_0173TBD_0178TBD_0177
STYP99287 STM3060STM3053STM3055STM3059STM3054
SSP94122 SHEWANA3_3505SHEWANA3_3499SHEWANA3_3501SHEWANA3_3504SHEWANA3_3500
SSON300269 SSO_3063SSO_3056SSO_3058SSO_3062SSO_3057
SSED425104 SSED_3679SSED_3673SSED_3675SSED_3678SSED_3674
SPRO399741 SPRO_3921SPRO_3914SPRO_3916SPRO_3920SPRO_3915
SPEA398579 SPEA_3308SPEA_3301SPEA_3303SPEA_3306SPEA_3302
SONE211586 SO_0775SO_0781SO_0779SO_0776SO_0780
SLOI323850 SHEW_3068SHEW_3062SHEW_3064SHEW_3067SHEW_3063
SHIGELLA YGFEGCVPGCVTYGFBGCVH
SHAL458817 SHAL_3379SHAL_3373SHAL_3375SHAL_3378SHAL_3374
SGLO343509 SG2007SG2000SG2002SG2006SG2001
SFLE373384 SFV_2958SFV_2951SFV_2953SFV_2957SFV_2952
SFLE198214 AAN44380.1AAN44373.1AAN44375.1AAN44379.1AAN44374.1
SENT454169 SEHA_C3293SEHA_C3285SEHA_C3287SEHA_C3292SEHA_C3286
SENT321314 SCH_3001SCH_2994SCH_2996SCH_3000SCH_2995
SENT295319 SPA2928SPA2921SPA2923SPA2927SPA2922
SENT220341 STY3216STY3209STY3211STY3215STY3210
SENT209261 T2978T2971T2973T2977T2972
SDYS300267 SDY_3171SDY_3178SDY_3176SDY_3172SDY_3177
SDEN318161 SDEN_0829SDEN_0835SDEN_0833SDEN_0830SDEN_0834
SDEG203122 SDE_3516SDE_2476SDE_0338SDE_0339
SBOY300268 SBO_3082SBO_3089SBO_3087SBO_3083SBO_3088
SBAL402882 SHEW185_3681SHEW185_3675SHEW185_3677SHEW185_3680SHEW185_3676
SBAL399599 SBAL195_3805SBAL195_3799SBAL195_3801SBAL195_3804SBAL195_3800
RPAL316058 RPB_4464RPB_3740RPB_3738RPB_3739
RPAL316055 RPE_4731RPE_1595RPE_1597RPE_1596
PSYR223283 PSPTO_1276PSPTO_0316PSPTO_5224PSPTO_0317
PSYR205918 PSYR_1096PSYR_0246PSYR_0320PSYR_0247
PSTU379731 PST_4062PST_4064PST_4071PST_4063
PSP56811 PSYCPRWF_1880PSYCPRWF_1725PSYCPRWF_1722PSYCPRWF_1878PSYCPRWF_1723
PPUT76869 PPUTGB1_5263PPUTGB1_3095PPUTGB1_5254PPUTGB1_5253
PPUT351746 PPUT_5110PPUT_1025PPUT_5101PPUT_5108PPUT_5100
PPUT160488 PP_5202PP_5192PP_5194PP_5201PP_5193
PPRO298386 PBPRA3120PBPRB1324PBPRA3119PBPRA3116
PMEN399739 PMEN_0322PMEN_1345PMEN_0331PMEN_0324PMEN_0332
PLUM243265 PLU3603PLU3596PLU3598PLU3602PLU3597
PING357804 PING_0604PING_2729PING_2726PING_0605PING_2728
PHAL326442 PSHAA0295PSHAA2473PSHAA2475PSHAA0561PSHAA2474
PFLU220664 PFL_5970PFL_5959PFL_5962PFL_5969PFL_5961
PFLU216595 PFLU5883PFLU4897PFLU5874PFLU5881PFLU5873
PFLU205922 PFL_5437PFL_5426PFL_5428PFL_5427
PENT384676 PSEEN5318PSEEN5307PSEEN5309PSEEN5308
PCRY335284 PCRYO_0803PCRYO_0806PCRYO_2051PCRYO_0805
PATL342610 PATL_3590PATL_3592PATL_3503PATL_3591
PARC259536 PSYC_0796PSYC_0799PSYC_1769PSYC_0798
PAER208964 PA5227PA5213PA5215PA5225PA5214
PAER208963 PA14_69030PA14_33000PA14_68870PA14_69010PA14_68860
NOCE323261 NOC_2576NOC_2547NOC_0500NOC_2578NOC_0907
NMUL323848 NMUL_A0626NMUL_A0210NMUL_A0214NMUL_A0213
NMEN374833 NMCC_0128NMCC_1587NMCC_0520NMCC_0521
NMEN272831 NMC2039NMC1594NMC0516NMC0517
NMEN122587 NMA0377NMA1934NMA0758NMA0759
NGON242231 NGO2023NGO1325NGO1406NGO1404
NEUR228410 NE1890NE0610NE0607NE0608
MSP400668 MMWYL1_1130MMWYL1_2285MMWYL1_2282MMWYL1_3758MMWYL1_2284
MCAP243233 MCA_2772MCA_0348MCA_0350MCA_2771MCA_0051
LPNE400673 LPC_0134LPC_0138LPC_0098LPC_0137
LPNE297246 LPP0128LPP0132LPP0090LPP0131
LPNE297245 LPL0113LPL0117LPL0078LPL0116
LPNE272624 LPG0114LPG0118LPG0076LPG0117
KPNE272620 GKPORF_B2700GKPORF_B2693GKPORF_B2695GKPORF_B2699GKPORF_B2694
ILOI283942 IL2100IL2092IL2094IL2099IL2093
HHAL349124 HHAL_1182HHAL_1194HHAL_1190HHAL_1184HHAL_1191
HCHE349521 HCH_01065HCH_03861HCH_03858HCH_01069HCH_05990
FTUL458234 FTA_0506FTA_0503FTA_0765FTA_0504
FTUL418136 FTW_1663FTW_1666FTW_0727FTW_1665
FTUL401614 FTN_0508FTN_0505FTN_1238FTN_0506
FTUL393115 FTF0410FTF0407FTF1219CFTF0408
FTUL393011 FTH_0478FTH_0475FTH_0727FTH_0476
FTUL351581 FTL_0480FTL_0477FTL_0725FTL_0478
FRANT GCVP2GCVTFT.1220CGCVH
FPHI484022 FPHI_0337FPHI_0340FPHI_1442FPHI_0339
ESP42895 ENT638_3329ENT638_3322ENT638_3324ENT638_3328ENT638_3323
EFER585054 EFER_2847EFER_2839EFER_2841EFER_2846EFER_2840
ECOO157 YGFEGCVPGCVTYGFBGCVH
ECOL83334 ECS3781ECS3774ECS3776ECS3780ECS3775
ECOL585397 ECED1_3369ECED1_3361ECED1_3363ECED1_3368ECED1_3362
ECOL585057 ECIAI39_3326ECIAI39_3318ECIAI39_3320ECIAI39_3325ECIAI39_3319
ECOL585056 ECUMN_3252ECUMN_3244ECUMN_3246ECUMN_3251ECUMN_3245
ECOL585055 EC55989_3198EC55989_3190EC55989_3192EC55989_3197EC55989_3191
ECOL585035 ECS88_3190ECS88_3182ECS88_3184ECS88_3189ECS88_3183
ECOL585034 ECIAI1_3029ECIAI1_3022ECIAI1_3024ECIAI1_3028ECIAI1_3023
ECOL481805 ECOLC_0799ECOLC_0806ECOLC_0804ECOLC_0800ECOLC_0805
ECOL469008 ECBD_0827ECBD_0834ECBD_0832ECBD_0828ECBD_0833
ECOL439855 ECSMS35_3044ECSMS35_3035ECSMS35_3037ECSMS35_3043ECSMS35_3036
ECOL413997 ECB_02742ECB_02735ECB_02737ECB_02741ECB_02736
ECOL409438 ECSE_3173ECSE_3166ECSE_3168ECSE_3172ECSE_3167
ECOL405955 APECO1_3618APECO1_3625APECO1_3623APECO1_3619APECO1_3624
ECOL364106 UTI89_C3297UTI89_C3288UTI89_C3290UTI89_C3295UTI89_C3289
ECOL362663 ECP_2903ECP_2896ECP_2898ECP_2902ECP_2897
ECOL331111 ECE24377A_3238ECE24377A_3230ECE24377A_3232ECE24377A_3237ECE24377A_3231
ECOL316407 ECK2905:JW2878:B2910ECK2898:JW2871:B2903ECK2900:JW2873:B2905ECK2904:JW5473:B2909ECK2899:JW2872:B2904
ECOL199310 C3492C3483C3485C3491C3484
ECAR218491 ECA0461ECA0745ECA0743ECA0460ECA0744
DNOD246195 DNO_0713DNO_1069DNO_1197DNO_0717DNO_1070
DARO159087 DARO_4027DARO_2465DARO_2463DARO_2464
CVIO243365 CV_0498CV_3429CV_3431CV_3430
CSAL290398 CSAL_0022CSAL_1811CSAL_1815CSAL_1812
CPSY167879 CPS_1268CPS_3846CPS_1274CPS_1270CPS_1275
CJAP155077 CJA_0291CJA_1061CJA_0421CJA_0293CJA_0420
CBUR434922 COXBU7E912_2038COXBU7E912_0293COXBU7E912_0289COXBU7E912_0290
CBUR360115 COXBURSA331_A0127COXBURSA331_A1900COXBURSA331_A1904COXBURSA331_A1903
CBUR227377 CBU_0067CBU_1713CBU_1716CBU_1715
ASP62928 AZO0634AZO1285AZO1287AZO1286
ASAL382245 ASA_2637ASA_2631ASA_2633ASA_2636ASA_2632
AHYD196024 AHA_1714AHA_1720AHA_1718AHA_1715AHA_1719
AEHR187272 MLG_2539MLG_2580MLG_2576MLG_2541MLG_2577
ABOR393595 ABO_2591ABO_2594ABO_2601ABO_2593
AAVE397945 AAVE_1535AAVE_3147AAVE_3145AAVE_3146


Organism features enriched in list (features available for 129 out of the 136 orgs in the list)
Feature    Pvalue       Num occurrences in list  Total num occurrences  
Arrangment:Chains 4.173e-7492
Arrangment:Pairs 0.001079137112
Arrangment:Singles 0.000580579286
Disease:Bubonic_plague 0.000107066
Disease:Dysentery 0.000107066
Disease:Gastroenteritis 0.00003021013
Disease:Legionnaire's_disease 0.002310944
Disease:Tularemia 0.000498955
Endospores:No 0.000012927211
GC_Content_Range4:0-40 3.001e-1413213
GC_Content_Range4:40-60 5.061e-1588224
GC_Content_Range7:30-40 1.422e-813166
GC_Content_Range7:40-50 0.004636636117
GC_Content_Range7:50-60 7.109e-1252107
Genome_Size_Range5:0-2 5.536e-118155
Genome_Size_Range5:2-4 0.000142427197
Genome_Size_Range5:4-6 1.244e-1883184
Genome_Size_Range9:1-2 6.508e-88128
Genome_Size_Range9:2-3 0.001331115120
Genome_Size_Range9:4-5 0.00001063896
Genome_Size_Range9:5-6 3.752e-114588
Gram_Stain:Gram_Neg 9.871e-28123333
Habitat:Multiple 0.000342355178
Habitat:Specialized 0.0024853453
Habitat:Terrestrial 0.0031993131
Motility:No 1.191e-712151
Motility:Yes 9.010e-1191267
Optimal_temp.:- 0.001462571257
Optimal_temp.:25-30 0.00237691019
Oxygen_Req:Anaerobic 3.117e-102102
Oxygen_Req:Facultative 2.831e-871201
Pathogenic_in:No 0.000013230226
Pathogenic_in:Plant 0.00019841015
Shape:Coccus 0.0001034682
Shape:Rod 2.090e-13111347
Shape:Spiral 0.0015876134
Temp._range:Psychrophilic 0.000034389
Temp._range:Thermophilic 0.0012533135



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ORGANISMS CONTAINING AT MOST 1 GENES FROM THE GROUP:

Total number of orgs: 192
Effective number of orgs (counting one per cluster within 468 clusters): 156

Organism list
Homologs in each organism in the list
Features enriched in organism list


Follow (ncbi) link, when present, to find the set of organism features for each organism
Org ID  Org Name  # genes in group found in org  
ZMOB264203 ncbi Zymomonas mobilis mobilis ZM40
WSUC273121 ncbi Wolinella succinogenes DSM 17400
WPIP955 Wolbachia pipientis0
WPIP80849 Wolbachia endosymbiont of Brugia malayi0
UURE95667 Ureaplasma urealyticum serovar 130
UURE95664 Ureaplasma urealyticum serovar 100
UPAR505682 ncbi Ureaplasma parvum serovar 3 str. ATCC 278150
UMET351160 ncbi uncultured methanogenic archaeon RC-I0
TPEN368408 ncbi Thermofilum pendens Hrk 50
TPAL243276 ncbi Treponema pallidum pallidum Nichols0
TDEN326298 ncbi Sulfurimonas denitrificans DSM 12510
STHE322159 ncbi Streptococcus thermophilus LMD-90
STHE299768 ncbi Streptococcus thermophilus CNRZ10660
STHE264199 ncbi Streptococcus thermophilus LMG 183110
SSUI391296 ncbi Streptococcus suis 98HAH330
SSUI391295 ncbi Streptococcus suis 05ZYH330
SSP387093 ncbi Sulfurovum sp. NBC37-10
SSOL273057 ncbi Sulfolobus solfataricus P21
SPYO370554 ncbi Streptococcus pyogenes MGAS107500
SPYO370553 ncbi Streptococcus pyogenes MGAS20960
SPYO370552 ncbi Streptococcus pyogenes MGAS102700
SPYO370551 ncbi Streptococcus pyogenes MGAS94290
SPYO319701 ncbi Streptococcus pyogenes MGAS61800
SPYO293653 ncbi Streptococcus pyogenes MGAS50050
SPYO286636 ncbi Streptococcus pyogenes MGAS103940
SPYO198466 ncbi Streptococcus pyogenes MGAS3150
SPYO193567 ncbi Streptococcus pyogenes SSI-10
SPYO186103 ncbi Streptococcus pyogenes MGAS82320
SPYO160490 ncbi Streptococcus pyogenes M1 GAS0
SPNE488221 ncbi Streptococcus pneumoniae 705850
SPNE487214 ncbi Streptococcus pneumoniae Hungary19A-60
SPNE487213 ncbi Streptococcus pneumoniae Taiwan19F-140
SPNE171101 ncbi Streptococcus pneumoniae R60
SPNE170187 ncbi Streptococcus pneumoniae G540
SPNE1313 Streptococcus pneumoniae0
SMUT210007 ncbi Streptococcus mutans UA1590
SGOR29390 Streptococcus gordonii Challis0
SFUM335543 ncbi Syntrophobacter fumaroxidans MPOB0
SAGA211110 ncbi Streptococcus agalactiae NEM3160
SAGA208435 ncbi Streptococcus agalactiae 2603V/R0
SAGA205921 ncbi Streptococcus agalactiae A9090
SACI56780 ncbi Syntrophus aciditrophicus SB0
SACI330779 ncbi Sulfolobus acidocaldarius DSM 6391
RTYP257363 ncbi Rickettsia typhi Wilmington0
RRIC452659 ncbi Rickettsia rickettsii Iowa0
RRIC392021 ncbi Rickettsia rickettsii Sheila Smith0
RPRO272947 ncbi Rickettsia prowazekii Madrid E0
RMAS416276 ncbi Rickettsia massiliae MTU50
RFEL315456 ncbi Rickettsia felis URRWXCal20
RCON272944 ncbi Rickettsia conorii Malish 70
RCAN293613 ncbi Rickettsia canadensis McKiel0
RBEL391896 ncbi Rickettsia bellii OSU 85-3890
RBEL336407 ncbi Rickettsia bellii RML369-C0
RALB246199 Ruminococcus albus 80
RAKA293614 ncbi Rickettsia akari Hartford0
PTHE370438 ncbi Pelotomaculum thermopropionicum SI0
PSP312153 ncbi Polynucleobacter necessarius asymbioticus QLW-P1DMWA-11
PPEN278197 ncbi Pediococcus pentosaceus ATCC 257450
PISL384616 ncbi Pyrobaculum islandicum DSM 41840
PCAR338963 ncbi Pelobacter carbinolicus DSM 23800
PAST100379 Onion yellows phytoplasma0
PARS340102 ncbi Pyrobaculum arsenaticum DSM 135140
PAER178306 ncbi Pyrobaculum aerophilum IM20
OTSU357244 ncbi Orientia tsutsugamushi Boryong0
NSP387092 ncbi Nitratiruptor sp. SB155-20
NSEN222891 ncbi Neorickettsia sennetsu Miyayama0
MTHE349307 ncbi Methanosaeta thermophila PT0
MTHE187420 ncbi Methanothermobacter thermautotrophicus Delta H0
MSYN262723 ncbi Mycoplasma synoviae 530
MSTA339860 ncbi Methanosphaera stadtmanae DSM 30910
MSED399549 ncbi Metallosphaera sedula DSM 53481
MPUL272635 ncbi Mycoplasma pulmonis UAB CTIP0
MPNE272634 ncbi Mycoplasma pneumoniae M1290
MPEN272633 ncbi Mycoplasma penetrans HF-20
MMYC272632 ncbi Mycoplasma mycoides mycoides SC str. PG10
MMOB267748 ncbi Mycoplasma mobile 163K0
MMAZ192952 ncbi Methanosarcina mazei Go10
MMAR444158 ncbi Methanococcus maripaludis C60
MMAR426368 ncbi Methanococcus maripaludis C70
MMAR402880 ncbi Methanococcus maripaludis C50
MMAR368407 ncbi Methanoculleus marisnigri JR10
MMAR267377 ncbi Methanococcus maripaludis S20
MLAB410358 ncbi Methanocorpusculum labreanum Z0
MKAN190192 ncbi Methanopyrus kandleri AV190
MJAN243232 ncbi Methanocaldococcus jannaschii DSM 26610
MHYO295358 ncbi Mycoplasma hyopneumoniae 2320
MHYO262722 ncbi Mycoplasma hyopneumoniae 74480
MHYO262719 ncbi Mycoplasma hyopneumoniae J0
MHUN323259 ncbi Methanospirillum hungatei JF-10
MGEN243273 ncbi Mycoplasma genitalium G370
MFLO265311 ncbi Mesoplasma florum L10
MCAP340047 ncbi Mycoplasma capricolum capricolum ATCC 273430
MBUR259564 ncbi Methanococcoides burtonii DSM 62420
MBAR269797 ncbi Methanosarcina barkeri Fusaro0
MART243272 ncbi Mycoplasma arthritidis 158L3-10
MAEO419665 ncbi Methanococcus aeolicus Nankai-30
MACE188937 ncbi Methanosarcina acetivorans C2A0
LXYL281090 ncbi Leifsonia xyli xyli CTCB070
LSAK314315 ncbi Lactobacillus sakei sakei 23K0
LREU557436 ncbi Lactobacillus reuteri DSM 200160
LPLA220668 ncbi Lactobacillus plantarum WCFS10
LMES203120 ncbi Leuconostoc mesenteroides mesenteroides ATCC 82930
LLAC272623 ncbi Lactococcus lactis lactis Il14030
LLAC272622 ncbi Lactococcus lactis cremoris SK110
LJOH257314 ncbi Lactobacillus johnsonii NCC 5330
LINT363253 ncbi Lawsonia intracellularis PHE/MN1-000
LHEL405566 ncbi Lactobacillus helveticus DPC 45710
LGAS324831 ncbi Lactobacillus gasseri ATCC 333230
LDEL390333 ncbi Lactobacillus delbrueckii bulgaricus ATCC 118420
LDEL321956 ncbi Lactobacillus delbrueckii bulgaricus ATCC BAA-3650
LCAS321967 ncbi Lactobacillus casei ATCC 3340
LBRE387344 ncbi Lactobacillus brevis ATCC 3670
LACI272621 ncbi Lactobacillus acidophilus NCFM0
JSP375286 ncbi Janthinobacterium sp. Marseille0
IHOS453591 ncbi Ignicoccus hospitalis KIN4/I0
HWAL362976 ncbi Haloquadratum walsbyi DSM 167900
HPYL85963 ncbi Helicobacter pylori J990
HPYL357544 ncbi Helicobacter pylori HPAG10
HPY ncbi Helicobacter pylori 266950
HMOD498761 ncbi Heliobacterium modesticaldum Ice10
HHEP235279 ncbi Helicobacter hepaticus ATCC 514490
HBUT415426 ncbi Hyperthermus butylicus DSM 54561
HARS204773 ncbi Herminiimonas arsenicoxydans0
HACI382638 ncbi Helicobacter acinonychis Sheeba0
GBET391165 ncbi Granulibacter bethesdensis CGDNIH10
FSUC59374 ncbi Fibrobacter succinogenes succinogenes S850
FNUC190304 ncbi Fusobacterium nucleatum nucleatum ATCC 255860
FMAG334413 ncbi Finegoldia magna ATCC 293281
ERUM302409 ncbi Ehrlichia ruminantium Gardel0
ERUM254945 ncbi Ehrlichia ruminantium Welgevonden0
EFAE226185 ncbi Enterococcus faecalis V5830
ECHA205920 ncbi Ehrlichia chaffeensis Arkansas0
ECAN269484 ncbi Ehrlichia canis Jake0
DSP255470 ncbi Dehalococcoides sp. CBDB10
DSP216389 ncbi Dehalococcoides sp. BAV10
DOLE96561 ncbi Desulfococcus oleovorans Hxd30
DETH243164 ncbi Dehalococcoides ethenogenes 1950
CTRA471473 ncbi Chlamydia trachomatis L2b/UCH-1/proctitis0
CTRA471472 ncbi Chlamydia trachomatis 434/Bu0
CTET212717 ncbi Clostridium tetani E880
CSUL444179 ncbi Candidatus Sulcia muelleri GWSS0
CPNE182082 ncbi Chlamydophila pneumoniae TW-1830
CPNE138677 ncbi Chlamydophila pneumoniae J1380
CPNE115713 ncbi Chlamydophila pneumoniae CWL0290
CPNE115711 ncbi Chlamydophila pneumoniae AR390
CPER289380 ncbi Clostridium perfringens SM1010
CPER195103 ncbi Clostridium perfringens ATCC 131240
CPER195102 ncbi Clostridium perfringens 130
CNOV386415 ncbi Clostridium novyi NT0
CMUR243161 ncbi Chlamydia muridarum Nigg0
CMET456442 ncbi Candidatus Methanoregula boonei 6A80
CMAQ397948 ncbi Caldivirga maquilingensis IC-1670
CJEJ407148 ncbi Campylobacter jejuni jejuni 811160
CJEJ360109 ncbi Campylobacter jejuni doylei 269.970
CJEJ354242 ncbi Campylobacter jejuni jejuni 81-1760
CJEJ195099 ncbi Campylobacter jejuni RM12210
CJEJ192222 ncbi Campylobacter jejuni jejuni NCTC 111680
CHOM360107 ncbi Campylobacter hominis ATCC BAA-3810
CGLU196627 ncbi Corynebacterium glutamicum ATCC 130320
CFET360106 ncbi Campylobacter fetus fetus 82-400
CFEL264202 ncbi Chlamydophila felis Fe/C-560
CEFF196164 ncbi Corynebacterium efficiens YS-3140
CDIP257309 ncbi Corynebacterium diphtheriae NCTC 131290
CDES477974 ncbi Candidatus Desulforudis audaxviator MP104C0
CCUR360105 ncbi Campylobacter curvus 525.920
CCON360104 ncbi Campylobacter concisus 138260
CCAV227941 ncbi Chlamydophila caviae GPIC0
CBOT508765 ncbi Clostridium botulinum B str. Eklund 17B0
CBLO291272 ncbi Candidatus Blochmannia pennsylvanicus BPEN1
CBLO203907 ncbi Candidatus Blochmannia floridanus1
CBEI290402 ncbi Clostridium beijerinckii NCIMB 80520
CACE272562 ncbi Clostridium acetobutylicum ATCC 8240
CABO218497 ncbi Chlamydophila abortus S26/30
BXEN266265 ncbi Burkholderia xenovorans LB4000
BTUR314724 ncbi Borrelia turicatae 91E1350
BSP107806 ncbi Buchnera aphidicola APS (Acyrthosiphon pisum)0
BLON206672 ncbi Bifidobacterium longum NCC27050
BHER314723 ncbi Borrelia hermsii DAH0
BGAR290434 ncbi Borrelia garinii PBi0
BCIC186490 Candidatus Baumannia cicadellinicola0
BBUR224326 ncbi Borrelia burgdorferi B310
BAPH372461 ncbi Buchnera aphidicola Cc (Cinara cedri)1
BAPH198804 ncbi Buchnera aphidicola Sg (Schizaphis graminum)0
BAFZ390236 ncbi Borrelia afzelii PKo0
AYEL322098 ncbi Aster yellows witches-broom phytoplasma AYWB0
AURANTIMONAS Aurantimonas manganoxydans SI85-9A10
APHA212042 ncbi Anaplasma phagocytophilum HZ0
APER272557 ncbi Aeropyrum pernix K11
AMAR234826 ncbi Anaplasma marginale St. Maries0
AFUL224325 ncbi Archaeoglobus fulgidus DSM 43040
ABUT367737 ncbi Arcobacter butzleri RM40180
AAEO224324 ncbi Aquifex aeolicus VF51


Names of the homologs of the genes in the group in each of these orgs
  EG12878   EG11810   EG11442   EG11323   EG10371   
ZMOB264203
WSUC273121
WPIP955
WPIP80849
UURE95667
UURE95664
UPAR505682
UMET351160
TPEN368408
TPAL243276
TDEN326298
STHE322159
STHE299768
STHE264199
SSUI391296
SSUI391295
SSP387093
SSOL273057 SSO0917
SPYO370554
SPYO370553
SPYO370552
SPYO370551
SPYO319701
SPYO293653
SPYO286636
SPYO198466
SPYO193567
SPYO186103
SPYO160490
SPNE488221
SPNE487214
SPNE487213
SPNE171101
SPNE170187
SPNE1313
SMUT210007
SGOR29390
SFUM335543
SAGA211110
SAGA208435
SAGA205921
SACI56780
SACI330779 SACI_1384
RTYP257363
RRIC452659
RRIC392021
RPRO272947
RMAS416276
RFEL315456
RCON272944
RCAN293613
RBEL391896
RBEL336407
RALB246199
RAKA293614
PTHE370438
PSP312153 PNUC_0030
PPEN278197
PISL384616
PCAR338963
PAST100379
PARS340102
PAER178306
OTSU357244
NSP387092
NSEN222891
MTHE349307
MTHE187420
MSYN262723
MSTA339860
MSED399549 MSED_1662
MPUL272635
MPNE272634
MPEN272633
MMYC272632
MMOB267748
MMAZ192952
MMAR444158
MMAR426368
MMAR402880
MMAR368407
MMAR267377
MLAB410358
MKAN190192
MJAN243232
MHYO295358
MHYO262722
MHYO262719
MHUN323259
MGEN243273
MFLO265311
MCAP340047
MBUR259564
MBAR269797
MART243272
MAEO419665
MACE188937
LXYL281090
LSAK314315
LREU557436
LPLA220668
LMES203120
LLAC272623
LLAC272622
LJOH257314
LINT363253
LHEL405566
LGAS324831
LDEL390333
LDEL321956
LCAS321967
LBRE387344
LACI272621
JSP375286
IHOS453591
HWAL362976
HPYL85963
HPYL357544
HPY
HMOD498761
HHEP235279
HBUT415426 HBUT_0181
HARS204773
HACI382638
GBET391165
FSUC59374
FNUC190304
FMAG334413 FMG_0462
ERUM302409
ERUM254945
EFAE226185
ECHA205920
ECAN269484
DSP255470
DSP216389
DOLE96561
DETH243164
CTRA471473
CTRA471472
CTET212717
CSUL444179
CPNE182082
CPNE138677
CPNE115713
CPNE115711
CPER289380
CPER195103
CPER195102
CNOV386415
CMUR243161
CMET456442
CMAQ397948
CJEJ407148
CJEJ360109
CJEJ354242
CJEJ195099
CJEJ192222
CHOM360107
CGLU196627
CFET360106
CFEL264202
CEFF196164
CDIP257309
CDES477974
CCUR360105
CCON360104
CCAV227941
CBOT508765
CBLO291272 BPEN_265
CBLO203907 BFL258
CBEI290402
CACE272562
CABO218497
BXEN266265
BTUR314724
BSP107806
BLON206672
BHER314723
BGAR290434
BCIC186490
BBUR224326
BAPH372461 BCC_258
BAPH198804
BAFZ390236
AYEL322098
AURANTIMONAS
APHA212042
APER272557 APE0951
AMAR234826
AFUL224325
ABUT367737
AAEO224324 AQ_1108


Organism features enriched in list (features available for 182 out of the 192 orgs in the list)
Feature    Pvalue       Num occurrences in list  Total num occurrences  
Arrangment:Chains 8.626e-85192
Arrangment:Pairs 0.006755125112
Disease:Pharyngitis 0.000081088
Disease:Wide_range_of_infections 2.217e-61111
Disease:bronchitis_and_pneumonitis 0.000081088
Endospores:No 1.543e-896211
Endospores:Yes 0.0071269953
GC_Content_Range4:0-40 3.643e-19115213
GC_Content_Range4:40-60 0.009747459224
GC_Content_Range4:60-100 1.570e-187145
GC_Content_Range7:0-30 2.334e-143947
GC_Content_Range7:30-40 1.207e-676166
GC_Content_Range7:50-60 0.001300921107
GC_Content_Range7:60-70 2.213e-167134
Genome_Size_Range5:0-2 8.606e-40115155
Genome_Size_Range5:4-6 5.805e-277184
Genome_Size_Range5:6-10 2.249e-7147
Genome_Size_Range9:0-1 2.616e-102427
Genome_Size_Range9:1-2 1.332e-2691128
Genome_Size_Range9:4-5 1.704e-11596
Genome_Size_Range9:5-6 2.109e-13288
Gram_Stain:Gram_Neg 3.004e-679333
Habitat:Host-associated 0.000023286206
Habitat:Terrestrial 0.0006962231
Motility:No 0.000062366151
Motility:Yes 2.344e-951267
Optimal_temp.:25-30 0.0064314119
Optimal_temp.:30-35 0.004251467
Optimal_temp.:37 0.000298848106
Oxygen_Req:Aerobic 1.924e-928185
Oxygen_Req:Anaerobic 2.285e-652102
Oxygen_Req:Microaerophilic 0.00145971218
Pathogenic_in:Swine 0.002853855
Salinity:Non-halophilic 0.004084144106
Shape:Coccus 0.00006214182
Shape:Irregular_coccus 0.00001391417
Shape:Rod 1.135e-1466347
Shape:Sphere 1.737e-61619
Shape:Spiral 0.00002792234



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ORGANISMS ENRICHED FOR GROUP:




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ORGANISMS DEPLETED FOR GROUP:




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PHYLOGENETIC PROFILE SIMILARITY WITH KNOWN PATHWAYS:

Pathways or complexes with absolute value of Pearson coefficient with respect to candidate larger than 0.4 are listed below
The candidate is assumed to exist in orgs listed in section List of organisms containing most genes from the group


Pathway or complex  # Orgs containing it  # of those orgs also containing candidate  Pearson Coeff  
AST-PWY (arginine degradation II (AST pathway))120840.5696
GLYCOCAT-PWY (glycogen degradation I)2461250.5668
PWY0-1241 (ADP-L-glycero-β-D-manno-heptose biosynthesis)2181160.5573
PWY4FS-7 (phosphatidylglycerol biosynthesis I (plastidic))2911320.5333
PWY-5111 (CMP-KDO biosynthesis II (from D-arabinose 5-phosphate))3001340.5328
PWY0-1319 (CDP-diacylglycerol biosynthesis II)2961320.5243
PWY-5918 (heme biosynthesis I)2721260.5220
PHOSLIPSYN-PWY (phospholipid biosynthesis I)2901300.5195
PWY-4041 (γ-glutamyl cycle)2791270.5165
COBALSYN-PWY (adenosylcobalamin salvage from cobinamide I)1951040.5148
PWY-1269 (CMP-KDO biosynthesis I)3251350.4982
HEME-BIOSYNTHESIS-II (heme biosynthesis from uroporphyrinogen-III I)2861260.4957
GLUTATHIONESYN-PWY (glutathione biosynthesis)3391360.4837
ECASYN-PWY (enterobacterial common antigen biosynthesis)191970.4661
NAGLIPASYN-PWY (lipid IVA biosynthesis)3481350.4619
PWY0-1329 (succinate to cytochrome bo oxidase electron transfer)96630.4525
PWY-5148 (acyl-CoA hydrolysis)2271050.4477
KDO-LIPASYN-PWY (KDO2-lipid A biosynthesis I)2251040.4440
PWY0-1182 (trehalose degradation II (trehalase))70510.4395
PWY-5386 (methylglyoxal degradation I)3051230.4385
PWY-5913 (TCA cycle variation IV)3011220.4377
LIPA-CORESYN-PWY (Lipid A-core biosynthesis)176890.4365
KDOSYN-PWY (KDO transfer to lipid IVA I)180900.4347
KDO-NAGLIPASYN-PWY (superpathway of KDO2-lipid A biosynthesis)179890.4287
P184-PWY (protocatechuate degradation I (meta-cleavage pathway))94600.4286
GLUCONSUPER-PWY (D-gluconate degradation)2291030.4272
PWY0-1299 (arginine dependent acid resistance)199940.4213
GALACTITOLCAT-PWY (galactitol degradation)73500.4115
ENTNER-DOUDOROFF-PWY (Entner-Doudoroff pathway I)2491060.4097
GLYCOLYSIS-E-D (superpathway of glycolysis and Entner-Doudoroff)2491060.4097
THREONINE-DEG2-PWY (threonine degradation II)214960.4033
PWY-5861 (superpathway of demethylmenaquinone-8 biosynthesis)50390.4017



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PAIRWISE GENOME CONTEXT SCORE MATRIX:

  EG11810   EG11442   EG11323   EG10371   
EG128780.9985350.9989810.9996190.998963
EG118100.999950.9987130.999948
EG114420.9991050.999968
EG113230.999075
EG10371



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PAIRWISE BLAST SCORES:

  EG12878   EG11810   EG11442   EG11323   EG10371   
EG128780.0f0----
EG11810-0.0f0---
EG11442--0.0f0--
EG11323---0.0f0-
EG10371----0.0f0



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PATHWAYS OR PROTEIN COMPLEX MATCHES IN TARGET ORG:

For each case, all genes involved in the pathway or complex are listed. For each gene we list: a tag indicating whether the gene is part of the candidate list or not, the average and the minimum scores of the gene to the candidate list, the gene name, and its product names.

- GLYCLEAV-PWY (glycine cleavage complex) (degree of match pw to cand: 0.750, degree of match cand to pw: 0.600, average score: 0.562)
  Genes in pathway or complex:
             0.2892 0.0722 EG10543 (lpd) E3-MONOMER (E3 monomer)
   *in cand* 0.9994 0.9985 EG11810 (gcvP) GCVP-MONOMER (glycine decarboxylase)
   *in cand* 0.9996 0.9990 EG11442 (gcvT) GCVT-MONOMER (aminomethyltransferase)
   *in cand* 0.9996 0.9990 EG10371 (gcvH) LIPOYL-GCVH (lipoyl-GcvH-protein)
  Genes in candidate but not in this pathway or complex:
   *in cand* 0.9993 0.9987 EG11323 (ygfB) EG11323-MONOMER (predicted protein)
   *in cand* 0.9992 0.9985 EG12878 (zapA) EG12878-MONOMER (protein that localizes to the cytokinetic ring)

- 1CMET2-PWY (formylTHF biosynthesis I) (degree of match pw to cand: 0.231, degree of match cand to pw: 0.600, average score: 0.595)
  Genes in pathway or complex:
             0.3341 0.1212 EG11819 (purU) FORMYLTHFDEFORMYL-MONOMER (formyltetrahydrofolate deformylase)
             0.7902 0.5081 EG10326 (folA) DIHYDROFOLATEREDUCT-MONOMER (dihydrofolate reductase)
             0.8765 0.7955 G6862 (folM) G6862-MONOMER (dihydromonapterin reductase / dihydrofolate reductase)
             0.4528 0.1992 EG10408 (glyA) GLYOHMETRANS-MONOMER (GlyA)
             0.4973 0.0690 EG10328 (folD) FOLD-MONOMER (FolD)
   *in cand* 0.9996 0.9990 EG11442 (gcvT) GCVT-MONOMER (aminomethyltransferase)
   *in cand* 0.9996 0.9990 EG10371 (gcvH) LIPOYL-GCVH (lipoyl-GcvH-protein)
   *in cand* 0.9994 0.9985 EG11810 (gcvP) GCVP-MONOMER (glycine decarboxylase)
             0.2892 0.0722 EG10543 (lpd) E3-MONOMER (E3 monomer)
             0.9511 0.9171 EG10585 (metF) METHYLENETHFREDUCT-MONOMER (MetF)
             0.6738 0.3407 EG10587 (metH) HOMOCYSMETB12-MONOMER (cobalamin-dependent methionine synthase)
             0.9847 0.9790 EG11002 (thyA) THYMIDYLATESYN-MONOMER (thymidylate synthase)
             0.2276 0.0640 EG10327 (folC) FOLC-MONOMER (bifunctional folypolyglutamate synthetase / dihydrofolate synthetase)
  Genes in candidate but not in this pathway or complex:
   *in cand* 0.9993 0.9987 EG11323 (ygfB) EG11323-MONOMER (predicted protein)
   *in cand* 0.9992 0.9985 EG12878 (zapA) EG12878-MONOMER (protein that localizes to the cytokinetic ring)
   This pathway has holes

- GCVMULTI-CPLX (glycine cleavage system) (degree of match pw to cand: 0.750, degree of match cand to pw: 0.600, average score: 0.562)
  Genes in pathway or complex:
   *in cand* 0.9996 0.9990 EG11442 (gcvT) GCVT-MONOMER (aminomethyltransferase)
   *in cand* 0.9996 0.9990 EG10371 (gcvH) LIPOYL-GCVH (lipoyl-GcvH-protein)
   *in cand* 0.9994 0.9985 EG11810 (gcvP) GCVP-MONOMER (glycine decarboxylase)
             0.2892 0.0722 EG10543 (lpd) E3-MONOMER (E3 monomer)
  Genes in candidate but not in this pathway or complex:
   *in cand* 0.9993 0.9987 EG11323 (ygfB) EG11323-MONOMER (predicted protein)
   *in cand* 0.9992 0.9985 EG12878 (zapA) EG12878-MONOMER (protein that localizes to the cytokinetic ring)



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GENOME CONTEXT INFORMATION:

Each row corresponds to a replicon in an organism, each column to a gene in the candidate. The second column indicates whether the organims was included in the list used to compute the genome context scores or not. Some organisms are not included because they are phylogenetically too similar to others already in the list.
The number in the matrix indicate the position of the homolog of the gene in the replicon. All numbers are relative to the smaller one, which is assigned a position of zero. Two columns with the same number indicate that the two genes matched the same gene in that organism.

Genome browser links for gene clusters

The links below opens a genome browser BioCyc page for each cluster of genes in the target genome. These pages shows the central gene of the cluster in the target genome and its best homolog in the reference genomes, for the genomes that contain homologs for at least 75% of the genes in the group. Only one genome per phylogenetic cluster of organisms is shown, to keep the list smaller.

EG10371 EG11442 EG11810 (centered at EG10371)
EG11323 EG12878 (centered at EG12878)


ORG:REPLICON:CIRC?\GENE  IN REF LIST  EG12878   EG11810   EG11442   EG11323   EG10371   
136/623405/623400/623130/623389/623
AAEO224324:0:Tyes----0
AAUR290340:2:Tyes-02959-2958
AAVE397945:0:Tyes015871585-1586
ABAC204669:0:Tyes-03-2
ABAU360910:0:Tyes-20-1
ABOR393595:0:Tyes-03102
ACAU438753:0:Tyes-40-1
ACEL351607:0:Tyes-0625-5
ACRY349163:8:Tyes-20-1
ADEH290397:0:Tyes-03-2
AEHR187272:0:Tyes04137238
AFER243159:0:Tyes-03-2
AHYD196024:0:Tyes06415
ALAI441768:0:Tyes-03--
AMAR329726:9:Tyes-43771-0
AMET293826:0:Tyes-01317-1318
ANAE240017:0:Tyes-21-0
AORE350688:0:Tyes-30-1
APER272557:0:Tyes----0
APLE416269:0:Tyes0--1-
APLE434271:0:Tno0--1-
ASAL382245:5:Tyes60251
ASP1667:3:Tyes-0--2
ASP232721:2:Tyes-02-1
ASP62928:0:Tyes0672674-673
ASP62977:0:Tyes---0718
ASP76114:2:Tyes-02-1
AVAR240292:3:Tyes-20--
BABO262698:0:Tno-1--0
BAMB339670:3:Tno-02-1
BAMB398577:3:Tno-02-1
BAMY326423:0:Tyes-02-701
BANT260799:0:Tno-02-752
BANT261594:2:Tno-02-733
BANT568206:2:Tyes-02-764
BANT592021:2:Tno-02-762
BAPH372461:0:Tyes0----
BBAC264462:0:Tyes-81-0
BBAC360095:0:Tyes-02-1
BBRO257310:0:Tyes-20-1
BCAN483179:0:Tno-02-1
BCEN331271:2:Tno-20-1
BCEN331272:3:Tyes-02-1
BCER226900:1:Tyes-02-751
BCER288681:0:Tno-02-757
BCER315749:1:Tyes-02-643
BCER405917:1:Tyes-02-797
BCER572264:1:Tno-02-756
BCLA66692:0:Tyes-02-503
BFRA272559:1:Tyes-7620-2841
BFRA295405:0:Tno-7260-3116
BHAL272558:0:Tyes-02-683
BHEN283166:0:Tyes-02-1
BJAP224911:0:Fyes-20-1
BLIC279010:0:Tyes-02-799
BMAL243160:1:Tno-02-1
BMAL320388:1:Tno-20-1
BMAL320389:1:Tyes-02-1
BMEL224914:0:Tno-1--0
BMEL359391:0:Tno-1--0
BOVI236:0:Tyes-0--1
BPAR257311:0:Tno-20-1
BPER257313:0:Tyes-20-1
BPET94624:0:Tyes-02-1
BPSE272560:1:Tyes-20-1
BPSE320372:1:Tno-20-1
BPSE320373:1:Tno-20-1
BPUM315750:0:Tyes-02-763
BQUI283165:0:Tyes-02-1
BSP36773:2:Tyes-02-1
BSP376:0:Tyes-20-1
BSUB:0:Tyes-02-877
BSUI204722:0:Tyes-02-1
BSUI470137:0:Tno-02-1
BTHA271848:1:Tno-02-1
BTHE226186:0:Tyes-03500-1401
BTHU281309:1:Tno-02-722
BTHU412694:1:Tno-02-691
BTRI382640:1:Tyes-02-1
BVIE269482:7:Tyes-02-1
BWEI315730:4:Tyes-02-749
CAULO:0:Tyes-03-2
CBLO203907:0:Tyes0----
CBLO291272:0:Tno0----
CBOT36826:1:Tno-30-1
CBOT441770:0:Tyes-30-1
CBOT441771:0:Tno-30-1
CBOT441772:1:Tno-30-1
CBOT498213:1:Tno-30-1
CBOT515621:2:Tyes-30-1
CBOT536232:0:Tno-30-1
CBUR227377:1:Tyes015801583-1582
CBUR360115:1:Tno016701673-1672
CBUR434922:2:Tno166930-1
CCHL340177:0:Tyes-20-75
CDIF272563:1:Tyes-954953-0
CHUT269798:0:Tyes-9742750-0
CHYD246194:0:Tyes-30-1
CJAP155077:0:Tyes07421302129
CJEI306537:0:Tyes-0--2
CKLU431943:1:Tyes-03-2
CKOR374847:0:Tyes-2820--
CMIC31964:2:Tyes-02--
CMIC443906:2:Tyes-02--
CPEL335992:0:Tyes-20-1
CPHY357809:0:Tyes-30--
CPRO264201:0:Fyes-30-1
CPSY167879:0:Tyes02498627
CRUT413404:0:Tyes-098-97
CSAL290398:0:Tyes018241828-1825
CSP501479:7:Fyes-20-1
CSP78:2:Tyes-04-3
CTEP194439:0:Tyes-490159-0
CVES412965:0:Tyes--1-0
CVIO243365:0:Tyes030043006-3005
DARO159087:0:Tyes156920-1
DDES207559:0:Tyes--312-0
DGEO319795:1:Tyes-20-1
DHAF138119:0:Tyes-03-2
DNOD246195:0:Tyes03354592336
DPSY177439:2:Tyes-0--2
DRAD243230:3:Tyes-0--2
DRED349161:0:Tyes-30-1
DSHI398580:5:Tyes-02-1
DVUL882:1:Tyes--257-0
ECAR218491:0:Tyes12902880289
ECOL199310:0:Tno90281
ECOL316407:0:Tno70261
ECOL331111:6:Tno80271
ECOL362663:0:Tno70261
ECOL364106:1:Tno90271
ECOL405955:2:Tyes70261
ECOL409438:6:Tyes70261
ECOL413997:0:Tno70261
ECOL439855:4:Tno90281
ECOL469008:0:Tno07516
ECOL481805:0:Tno07516
ECOL585034:0:Tno70261
ECOL585035:0:Tno70261
ECOL585055:0:Tno70261
ECOL585056:2:Tno70261
ECOL585057:0:Tno70261
ECOL585397:0:Tno70261
ECOL83334:0:Tno70261
ECOLI:0:Tno70261
ECOO157:0:Tno70261
EFER585054:1:Tyes70261
ELIT314225:0:Tyes-03-2
ESP42895:1:Tyes70261
FALN326424:0:Tyes-40722830-0
FJOH376686:0:Tyes-02151-1224
FMAG334413:1:Tyes--0--
FNOD381764:0:Tyes-02-46
FPHI484022:1:Tyes-0311512
FRANT:0:Tno-307381
FSP106370:0:Tyes-25861650-0
FSP1855:0:Tyes-01129-4278
FTUL351581:0:Tno-302261
FTUL393011:0:Tno-302131
FTUL393115:0:Tyes-307341
FTUL401614:0:Tyes-307281
FTUL418136:0:Tno-7617640763
FTUL458234:0:Tno-302261
GFOR411154:0:Tyes-26921315-0
GKAU235909:1:Tyes-02-598
GMET269799:1:Tyes-21672170-0
GOXY290633:5:Tyes-1--0
GSUL243231:0:Tyes-30-1
GTHE420246:1:Tyes-02-594
GURA351605:0:Tyes-03-2
GVIO251221:0:Tyes-03324--
HAUR316274:2:Tyes-30-1
HBUT415426:0:Tyes----0
HCHE349521:0:Tyes02668266544750
HDUC233412:0:Tyes0--1-
HHAL349124:0:Tyes012829
HINF281310:0:Tyes39--0-
HINF374930:0:Tyes0--40-
HINF71421:0:Tno40--0-
HMAR272569:8:Tyes--1-0
HMUK485914:1:Tyes--0-1
HNEP81032:0:Tyes-2--0
HSAL478009:4:Tyes--1-0
HSOM205914:1:Tyes1--0-
HSOM228400:0:Tno1--0-
HSP64091:2:Tno--1-0
ILOI283942:0:Tyes80271
JSP290400:1:Tyes-20-1
KPNE272620:2:Tyes70261
KRAD266940:2:Fyes-9790-972
LBIF355278:2:Tyes-20--
LBIF456481:2:Tno-20--
LBOR355276:1:Tyes-02-1
LBOR355277:1:Tno-20-1
LCHO395495:0:Tyes-02-1
LINN272626:1:Tno-20-1181
LINT189518:1:Tyes-02--
LINT267671:1:Tno-02--
LMON169963:0:Tno-20-1128
LMON265669:0:Tyes-20-1022
LPNE272624:0:Tno-3842041
LPNE297245:1:Fno-3438037
LPNE297246:1:Fyes-3741040
LPNE400673:0:Tno-3640039
LSPH444177:1:Tyes-02--
LWEL386043:0:Tyes-20-1009
MABS561007:1:Tyes-4610-456
MAER449447:0:Tyes-02014--
MAQU351348:2:Tyes2597--25910
MAVI243243:0:Tyes-6010-606
MBOV233413:0:Tno-6377-0
MBOV410289:0:Tno-6365-0
MCAP243233:0:Tyes258128929125800
MEXT419610:0:Tyes-02-1
MFLA265072:0:Tyes0---101
MGIL350054:3:Tyes-4590-464
MLEP272631:0:Tyes-7570-762
MLOT266835:2:Tyes-20-1
MMAG342108:0:Tyes-30-1
MMAR394221:0:Tyes-0--2
MPET420662:1:Tyes-02-1
MSED399549:0:Tyes----0
MSME246196:0:Tyes-0629-6
MSP164756:1:Tno-0476-7
MSP164757:0:Tno-0456-5
MSP189918:2:Tyes-0495-5
MSP266779:3:Tyes-02-1
MSP400668:0:Tyes01175117226711174
MSP409:2:Tyes-20-1
MSUC221988:0:Tyes0--1-
MTBCDC:0:Tno-5407-0
MTBRV:0:Tno-6386-0
MTHE264732:0:Tyes-03-2
MTUB336982:0:Tno-5379-0
MTUB419947:0:Tyes-6397-0
MVAN350058:0:Tyes-0442-5
MXAN246197:0:Tyes-20-1
NARO279238:0:Tyes-30-1
NEUR228410:0:Tyes129930-1
NEUT335283:2:Tyes-03-2
NFAR247156:2:Tyes-8030-798
NGON242231:0:Tyes655075-73
NHAM323097:2:Tyes-02-1
NMEN122586:0:Tno1429-0-1
NMEN122587:0:Tyes01473357-358
NMEN272831:0:Tno13329360-1
NMEN374833:0:Tno01436383-384
NMUL323848:3:Tyes41504-3
NOCE323261:1:Tyes2042201202044401
NPHA348780:2:Tyes--1-0
NSP103690:6:Tyes-02--
NSP35761:1:Tyes-4090-414
NWIN323098:0:Tyes-02-1
OANT439375:4:Tyes-02-1
OCAR504832:0:Tyes-02-1
OIHE221109:0:Tyes-02-497
PABY272844:0:Tyes-967276-0
PACN267747:0:Tyes-02-1
PAER208963:0:Tyes29440293229422931
PAER208964:0:Tno1402121
PARC259536:0:Tyes-039842
PATL342610:0:Tyes-8890089
PCRY335284:1:Tyes-0312422
PDIS435591:0:Tyes-1550-2844
PENT384676:0:Tyes1102-1
PFLU205922:0:Tyes1102-1
PFLU216595:1:Tyes9670958965957
PFLU220664:0:Tyes1103102
PFUR186497:0:Tyes-6810-157
PGIN242619:0:Tyes-302523-0
PHAL326442:1:Tyes0221622182682217
PHOR70601:0:Tyes-9000-183
PING357804:0:Tyes01985198211984
PINT246198:1:Tyes-40-1
PLUM243265:0:Fyes70261
PLUT319225:0:Tyes-0267-1452
PMAR146891:0:Tyes-020--
PMAR167539:0:Tyes-023--
PMAR167540:0:Tyes-020--
PMAR167542:0:Tyes-019--
PMAR167546:0:Tyes-019--
PMAR167555:0:Tyes-024--
PMAR59920:0:Tno-023--
PMAR74546:0:Tyes-021--
PMAR74547:0:Tyes-047--
PMAR93060:0:Tyes-020--
PMEN399739:0:Tyes01033829
PMOB403833:0:Tyes-20--
PMUL272843:1:Tyes0--1-
PNAP365044:8:Tyes-20-1
PPRO298386:1:Tyes-0---
PPRO298386:2:Tyes4--30
PPUT160488:0:Tno100291
PPUT351746:0:Tyes41090410041074099
PPUT76869:0:Tno218802179-2178
PRUM264731:0:Tyes--1-0
PSP117:0:Tyes-03--
PSP296591:2:Tyes-02-1
PSP312153:0:Tyes----0
PSP56811:2:Tyes164301621
PSTU379731:0:Tyes-0291
PSYR205918:0:Tyes-8430731
PSYR223283:2:Tyes-953048521
PTOR263820:0:Tyes-6930--
RCAS383372:0:Tyes-04-3
RDEN375451:4:Tyes-1--0
RETL347834:5:Tyes-1--0
REUT264198:3:Tyes-20-1
REUT381666:2:Tyes-20-1
RFER338969:1:Tyes-20-1
RLEG216596:6:Tyes-10--
RMET266264:2:Tyes-20-1
RPAL258594:0:Tyes-20-1
RPAL316055:0:Tyes310602-1
RPAL316056:0:Tyes-02-1
RPAL316057:0:Tyes-02-1
RPAL316058:0:Tyes72520-1
RPOM246200:0:Tyes-20--
RPOM246200:1:Tyes----0
RRUB269796:1:Tyes-03-2
RSAL288705:0:Tyes-01-810
RSOL267608:1:Tyes-20-1
RSP101510:3:Fyes-20152016-0
RSP357808:0:Tyes-04-3
RSPH272943:4:Tyes-20-1
RSPH349101:2:Tno-20-1
RSPH349102:5:Tyes-0--1
RXYL266117:0:Tyes-21-0
SACI330779:0:Tyes----0
SALA317655:1:Tyes-04-3
SARE391037:0:Tyes-0996-6
SAUR158878:1:Tno-704706-0
SAUR158879:1:Tno-632634-0
SAUR196620:0:Tno-704706-0
SAUR273036:0:Tno-626628-0
SAUR282458:0:Tno-731733-0
SAUR282459:0:Tno-704706-0
SAUR359786:1:Tno-756758-0
SAUR359787:1:Tno-769771-0
SAUR367830:3:Tno-699701-0
SAUR418127:0:Tyes-696698-0
SAUR426430:0:Tno-666668-0
SAUR93061:0:Fno-758760-0
SAUR93062:1:Tno-698700-0
SAVE227882:1:Fyes-42870-1
SBAL399599:3:Tyes60251
SBAL402882:1:Tno60251
SBOY300268:1:Tyes07516
SCO:2:Fyes-04148-4147
SDEG203122:0:Tyes320921650-1
SDEN318161:0:Tyes06415
SDYS300267:1:Tyes07516
SELO269084:0:Tyes-2570-258
SENT209261:0:Tno70261
SENT220341:0:Tno70261
SENT295319:0:Tno70261
SENT321314:2:Tno70261
SENT454169:2:Tno80271
SEPI176279:1:Tyes-599601-0
SEPI176280:0:Tno-627629-0
SERY405948:0:Tyes-33005079-0
SFLE198214:0:Tyes70261
SFLE373384:0:Tno70261
SGLO343509:3:Tyes70261
SHAE279808:0:Tyes-20-675
SHAL458817:0:Tyes60251
SHIGELLA:0:Tno70261
SLAC55218:1:Fyes-20-1
SLOI323850:0:Tyes60251
SMAR399550:0:Tyes-5--0
SMED366394:3:Tyes-02-1
SMEL266834:2:Tyes-02-1
SONE211586:1:Tyes06415
SPEA398579:0:Tno70251
SPRO399741:1:Tyes70261
SRUB309807:1:Tyes-0356--
SSAP342451:2:Tyes-20-654
SSED425104:0:Tyes60251
SSOL273057:0:Tyes-0---
SSON300269:1:Tyes70261
SSP1131:0:Tyes-058--
SSP1148:0:Tyes-0152--
SSP292414:2:Tyes-02-1
SSP321327:0:Tyes-1538722-0
SSP321332:0:Tyes-0988-209
SSP644076:6:Fyes-03-2
SSP64471:0:Tyes-064--
SSP84588:0:Tyes-052--
SSP94122:1:Tyes60251
STHE292459:0:Tyes-03-2
STOK273063:0:Tyes--1-0
STRO369723:0:Tyes-0928-6
STYP99287:1:Tyes70261
SWOL335541:0:Tyes-03-2
TACI273075:0:Tyes-13590-1368
TCRU317025:0:Tyes---0295
TDEN243275:0:Tyes-03--
TDEN292415:0:Tyes259205-4
TELO197221:0:Tyes-8690--
TERY203124:0:Tyes-26590--
TFUS269800:0:Tyes-0965-966
TKOD69014:0:Tyes-12481925-0
TLET416591:0:Tyes-03-2
TMAR243274:0:Tyes-30-1
TPET390874:0:Tno-03-2
TPSE340099:0:Tyes-30-1
TROS309801:1:Tyes-0565-566
TSP1755:0:Tyes-03-2
TSP28240:0:Tyes-03-2
TTEN273068:0:Tyes-196199-0
TTHE262724:1:Tyes-30-1
TTHE300852:2:Tyes-30-1
TTUR377629:0:Tyes393280411
TVOL273116:0:Tyes-2460-236
TWHI203267:0:Tyes-0539--
TWHI218496:0:Tno-0492--
VCHO:0:Tyes2--0-
VCHO:1:Fyes----0
VCHO345073:0:Tno-60-4
VCHO345073:1:Tno1--0-
VEIS391735:1:Tyes8061--0
VFIS312309:1:Tyes-30-2
VFIS312309:2:Tyes1--0-
VPAR223926:0:Tyes-04-1
VPAR223926:1:Tyes2--0-
VVUL196600:1:Tyes-05-1
VVUL196600:2:Tyes1--0-
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